Serum cholesterol levels preceding to suicide death in Japanese workers: a nested case-control study

被引:5
|
作者
Chen, Sanmei [1 ]
Mizoue, Tetsuya [1 ]
Hu, Huanhuan [1 ]
Kuwahara, Keisuke [1 ,2 ]
Honda, Toru [3 ]
Yamamoto, Shuichiro [3 ]
Nakagawa, Tohru [3 ]
Miyamoto, Toshiaki [4 ]
Okazaki, Hiroko [5 ]
Shimizu, Makiko [13 ]
Murakami, Taizo [13 ]
Eguchi, Masafumi [6 ]
Kochi, Takeshi [6 ]
Yamamoto, Makoto [7 ]
Ogasawara, Takayuki [14 ]
Sasaki, Naoko [14 ]
Uehara, Akihiko [8 ]
Imai, Teppei [9 ]
Nishihara, Akiko [10 ]
Hori, Ai [11 ]
Nagahama, Satsue [12 ]
Tomita, Kentaro [1 ]
Konishi, Maki [1 ]
Kabe, Isamu [6 ]
Dohi, Seitaro [5 ]
机构
[1] Natl Ctr Global Hlth & Med, Dept Epidemiol & Prevent, Tokyo, Japan
[2] Teikyo Univ, Grad Sch Publ Hlth, Tokyo, Japan
[3] Hitachi Ltd, Ibaraki, Japan
[4] Nippon Steel & Sumitomo Met Corp Kimitsu Works, Chiba, Japan
[5] Mitsui Chem Inc, Tokyo, Japan
[6] Furukawa Elect Corp Ltd, Tokyo, Japan
[7] Yamaha Corp, Shizuoka, Japan
[8] Seijinkai Shizunai Hosp, Shinhidaka, Hokkaido, Japan
[9] Azbil Corp, Tokyo, Japan
[10] Univ Tsukuba, Dept Global Publ Hlth, Ibaraki, Japan
[11] All Japan Labour Welf Fdn, Tokyo, Japan
[12] Mitsubishi Plast Inc, Tokyo, Japan
[13] Mizue Med Clin, Keihin Occupat Hlth Ctr, Tokyo, Kanagawa, Japan
[14] Mitsubishi Fuso Truck & Bus Corp, Kawasaki, Kanagawa, Japan
来源
ACTA NEUROPSYCHIATRICA | 2019年 / 31卷 / 05期
基金
日本学术振兴会;
关键词
suicide; cholesterol; nested case-control study; working population; RISK-FACTORS; LIPID LEVELS; MORTALITY; MEN; COHORT;
D O I
10.1017/neu.2019.26
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Objective: To investigate the association between suicide death and serum cholesterol levels as measured at times close to suicide death. Methods: We conducted a nested case-control study of 41 cases of suicide deaths and 205 matched controls with serum total cholesterol (TC) levels till 3 years before suicide death in a large cohort of Japanese workers. Results: Individuals in the lowest versus highest tertile/predefined category of TC in a Japanese working population had a three- to four-fold greater risk of suicide death. Each 10 mg/dl decrement of average TC was associated with an 18% increased chance of suicide death (95% confidence interval, 2-35%). Similar results were found for TC levels at each year. Conclusion: These results suggest that a low serum TC level in recent past is associated with an increased risk of suicide death.
引用
收藏
页码:266 / 269
页数:4
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