Total Synthesis of Emericellamide A: A Secondary Metabolite of Marine Cyclic Depsipeptide with Antimicrobial Properties

被引：23
|
作者：
Ma, Jing-Yi [1 ]
Xu, Long-Fei [1 ]
Huang, Wen-Feng [1 ]
Wei, Bang-Guo [1 ]
Lin, Guo-Qiang [1 ,2 ]
机构：
[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
[2] Fudan Univ, Inst Biomed Sci, Shanghai 200032, Peoples R China
来源：
SYNLETT | 2009年 / 08期
基金：
中国国家自然科学基金;
关键词：
cyclic depsipeptide; macrolactamization; antifungal agents; emericellamide; total synthesis; REAGENT; ACIDS;
D O I：
10.1055/s-0029-1217158
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Emericellamide A is a secondary metabolite of marine cyclic depsipeptide from the co-culture of the marine-derived fungus Emericella sp. and actinomycete Salinispora arenicola. A general method for the total synthesis of emericellamide A is depicted in this report.
引用
收藏
页码：1307 / 1310
页数：4
相关论文
共 50 条
  • [41] Isolation and Total Synthesis of PM170453, a New Cyclic Depsipeptide Isolated from Lyngbya sp.
    Fernandez, Rogelio
    Perez, Marta
    Losada, Alejandro
    Reboredo, Silvia
    Gomez-San Juan, Asier
    Martin, Maria Jesus
    Francesch, Andres
    Munt, Simon
    Cuevas, Carmen
    MARINE DRUGS, 2024, 22 (07)
  • [42] Isolation and Total Synthesis of Kinenzoline, an Antitrypanosomal Linear Depsipeptide Isolated from a Marine Salileptolyngbya sp. Cyanobacterium
    Kurisawa, Naoaki
    Otomo, Keisuke
    Iwasaki, Arihiro
    Jeelani, Ghulam
    Nozaki, Tomoyoshi
    Suenaga, Kiyotake
    JOURNAL OF ORGANIC CHEMISTRY, 2021, 86 (18): : 12528 - 12536
  • [43] Total synthesis of antimicrobial ISO branched marine fatty acids.
    Carballeira, NM
    Reyes, ED
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 213 : 627 - ORGN
  • [44] Total Synthesis of Marine Cyclic Enol-Phosphotriester Salinipostin Compounds
    Zhao Mingliang
    Wei Xianfeng
    Liu Xuemeng
    Dong Xueyang
    Yu Rilei
    Wan Shengbiao
    Jiang Tao
    JOURNAL OF OCEAN UNIVERSITY OF CHINA, 2018, 17 (03) : 683 - 689
  • [45] Total Synthesis of Marine Cyclic Enol-Phosphotriester Salinipostin Compounds
    ZHAO Mingliang
    WEI Xianfeng
    LIU Xuemeng
    DONG Xueyang
    YU Rilei
    WAN Shengbiao
    JIANG Tao
    Journal of Ocean University of China, 2018, 17 (03) : 683 - 689
  • [46] Total Synthesis of Marine Cyclic Enol-Phosphotriester Salinipostin Compounds
    Mingliang Zhao
    Xianfeng Wei
    Xuemeng Liu
    Xueyang Dong
    Rilei Yu
    Shengbiao Wan
    Tao Jiang
    Journal of Ocean University of China, 2018, 17 : 683 - 689
  • [47] Biosynthesis and Total Synthesis of Pyrronazol B: a Secondary Metabolite from Nannocystis pusilla
    Witte, Swjatoslaw N. R.
    Hug, Joachim J.
    Geraldy, Magalie N. E.
    Mueller, Rolf
    Kalesse, Markus
    CHEMISTRY-A EUROPEAN JOURNAL, 2017, 23 (63) : 15917 - 15921
  • [48] Structural Revision of Natural Cyclic Depsipeptide MA026 Established by Total Synthesis and Biosynthetic Gene Cluster Analysis
    Uchiyama, Chihiro
    Fukuda, Akane
    Mukaiyama, Minagi
    Nakazawa, Yoshiki
    Kuramochi, Yuka
    Muguruma, Kyohei
    Arimoto, Mitsue
    Ninomiya, Akihiro
    Kako, Koichiro
    Katsuyama, Yohei
    Konno, Sho
    Taguchi, Akihiro
    Takayama, Kentaro
    Taniguchi, Atsuhiko
    Nagumo, Yoko
    Usui, Takeo
    Hayashi, Yoshio
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (16) : 8792 - 8797
  • [49] Antimicrobial properties and the influence of temperature on secondary metabolite production in cold environment soil fungi
    Yogabaanu, U.
    Weber, Jean-Frederic Faizal
    Convey, Peter
    Rizman-Idid, Mohammed
    Alias, Siti Aisyah
    POLAR SCIENCE, 2017, 14 : 60 - 67
  • [50] Synthesis and antimicrobial properties of cyclic fluorodiamines containing boronate esters
    Zhu, Diya
    Hunter, Carmanah D.
    Baird, Samuel R.
    Davis, Bradley R.
    Bos, Allyson
    Geier, Stephen J.
    Vogels, Christopher M.
    Decken, Andreas
    Gray, Christopher A.
    Westcott, Stephen A.
    HETEROATOM CHEMISTRY, 2017, 28 (06)
12345