Total Synthesis of Emericellamide A: A Secondary Metabolite of Marine Cyclic Depsipeptide with Antimicrobial Properties

被引：23

作者：

Ma, Jing-Yi ^{[1
]}

Xu, Long-Fei ^{[1
]}

Huang, Wen-Feng ^{[1
]}

Wei, Bang-Guo ^{[1
]}

Lin, Guo-Qiang ^{[1
,2
]}

机构：

[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China

[2] Fudan Univ, Inst Biomed Sci, Shanghai 200032, Peoples R China

来源：

SYNLETT | 2009年 / 08期

基金：

中国国家自然科学基金;

关键词：

cyclic depsipeptide; macrolactamization; antifungal agents; emericellamide; total synthesis; REAGENT; ACIDS;

D O I：

10.1055/s-0029-1217158

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Emericellamide A is a secondary metabolite of marine cyclic depsipeptide from the co-culture of the marine-derived fungus Emericella sp. and actinomycete Salinispora arenicola. A general method for the total synthesis of emericellamide A is depicted in this report.

引用

页码：1307 / 1310

页数：4

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