Preparation and antimicrobial activity of 3-(p(2',5'-dibromobenzenesulphonamido)-phenyl)-5-aryl-1H/acetyl/phenyl-2-pyrazolines

被引：0
|
作者：
Sorathiya, SD [1 ]
Patel, VB [1 ]
Parikh, AR [1 ]
机构：
[1] SAURASHTRA UNIV,DEPT CHEM,RAJKOT 360005,GUJARAT,INDIA
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1997年 / 36卷 / 07期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The substituted 2-propen-1-ones 2a-h obtained from p-(2, 5-dibromobenzenesulpohonamido)-acetophenone 1 have been treated with hydrazine hydrate in ethanol and gl. acetic acid giving the expected 3-(p-(2', 5'-dibromobenzenesulphonamido)-phenyl)-5- aryl-1H/acetyl pyrazolin 3a-h and 4a-h. The same compound 2a-h on reaction with phenyl hydrazine gives 3-(p-(2', 5'-dibromo-benzenesulphonamido)phenyl)-5-aryl-1-phenyl-pyrazolines 5a-h. The structures have been supported by elemental analyses and IR, PMR and mass spectral data. The products have been screened for their antimicrobial activity.
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页码：630 / 632
页数：3
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