A ratiometric fluorescent probe for monitoring pH fluctuations during autophagy in living cells

被引：38
|
作者：
Wang, Shan [1 ,2 ]
Wang, Bingya [2 ]
Zhu, Lei [1 ]
Hou, Ji-Ting [2 ]
Yu, Kang-Kang [3 ]
机构：
[1] Hubei Engn Univ, Sch Chem & Mat Sci, Xiaogan 432000, Peoples R China
[2] Xinyang Normal Univ, Coll Chem & Chem Engn, Xinyang 464000, Peoples R China
[3] Sichuan Univ, Coll Life Sci, Key Lab Bioresources & Ecoenvironm, Minist Educ, Chengdu 610064, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 12期
基金：
中国国家自然科学基金;
关键词：
Cell death - Fluorescence;
D O I：
10.1039/d0cc07788g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present a ratiometric fluorescent probe for monitoring pH featuring superb photostability and chemostability. The down-regulation of the intracellular pH during autophagy in living cells induced by various stimuli, including several drugs and starvation, was quantified, which could provide instructive value to construct autophagy models to study the related pathological processes.
引用
收藏
页码：1510 / 1513
页数：4
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