Rat Hepatitis E Virus Linked to Severe Acute Hepatitis in an Immunocompetent Patient

被引：138

作者：

Andonov, Anton ^{[1
]}

Robbins, Mark ^{[2
]}

Borlang, Jamie ^{[1
]}

Cao, Jingxin ^{[1
]}

Hatchette, Todd ^{[3
,5
]}

Stueck, Ashley ^{[3
,5
]}

Deschambault, Yvon ^{[1
]}

Murnaghan, Kyle ^{[4
]}

Varga, Jessy ^{[1
]}

Johnston, Lynn ^{[4
]}

机构：

[1] Publ Hlth Agcy Canada, Natl Microbiol Lab, Winnipeg, MB, Canada

[2] Nova Scotia Hlth Author, Div Infect Dis, Halifax, NS, Canada

[3] Nova Scotia Hlth Author, Dept Pathol & Lab Med, Halifax, NS, Canada

[4] Nova Scotia Hlth Author, Dept Med, Halifax, NS, Canada

[5] Dalhousie Univ, Dept Pathol, Halifax, NS, Canada

来源：

JOURNAL OF INFECTIOUS DISEASES | 2019年 / 220卷 / 06期

关键词：

hepatitis E virus; Hepeviridae; phylogenetic analysis; Western blot; immunocompetent; INFECTION; FAMILY;

D O I：

10.1093/infdis/jiz025

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Hepatitis E virus (HEV) is a major public health concern in developing countries where the primary transmission is via contaminated water. Zoonotic HEV cases have been increasingly described in Europe, Japan, and the United States, with pigs representing the main animal reservoir of infection. We report an unusual acute hepatitis infection in a previously healthy man caused by a rat HEV with a considerably divergent genomic sequence compared with other rat HEV strains. It is possible that rat HEV is an underrecognized cause of hepatitis infection, and further studies are necessary to elucidate its potential risk and mode of transmission.

引用

页码：951 / 955

页数：5

共 50 条

[21] Hepatitis E virus as a Cause of Acute Hepatitis in The Netherlands
Tholen, Aletta T. R.
Schinkel, Janke
Molenkamp, Richard
Ang, C. Wim
PLOS ONE, 2016, 11 (02):
[22] Chronic Hepatitis E in an Immunocompetent Patient: A Case Report
Grewal, Priya
Kamili, Saleem
Motamed, David
HEPATOLOGY, 2014, 59 (01) : 347 - 348
[23] Detection of hepatitis E virus in acute hepatitis in Siberia
E. V. Chausov
V. A. Ternovoi
G. V. Kochneva
V. A. Svyatchenko
G. F. Sivolobova
A. A. Grazhdantseva
N. N. Kiselev
E. G. Sakharova
S. V. Netesov
Molecular Genetics, Microbiology and Virology, 2007, 22 (3) : 131 - 136
[24] HEPATITIS-E VIRUS AND ACUTE HEPATITIS IN ARGENTINA
GONZALEZ, J
ALONSO, A
FAINBOIM, H
RAMONET, M
CIOCCA, M
SCHRODER, T
VELASCO, C
MENDEZ, N
MARCHESINI, N
CARCHIO, E
EPOSTO, M
HEPATOLOGY, 1994, 19 (04) : I68 - I68
[25] Acute cytomegalovirus hepatitis in an immunocompetent patient: A case report
Jack P Wang
Bou-Zenn Lin
Chih-Lin Lin
Kuan-Yang Chen
Tsung-Jung Lin
World Journal of Clinical Cases, 2022, 10 (34) : 12605 - 12609
[26] Acute cytomegalovirus hepatitis in an immunocompetent patient: A case report
Wang, Jack P.
Lin, Bou-Zenn
Lin, Chih-Lin
Chen, Kuan-Yang
Lin, Tsung-Jung
WORLD JOURNAL OF CLINICAL CASES, 2022, 10 (34) : 12605 - 12609
[27] Herpes Simplex Virus (HSV) Hepatitis and Acute Liver Failure in a Seemingly Immunocompetent Patient
Kaspar, Matt
Caire, M. Thure
Bangarulingam, Sanjay
Bouneva, Iliana
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2013, 108 : S317 - S317
[28] Severe acute hepatitis in a burns patient
Nugent, N
McCormick, PA
Orr, D
BURNS, 2004, 30 (06) : 610 - 611
[29] Acute hepatitis E infection associated with Guillain-Barre syndrome in an immunocompetent patient
Comont, T.
Bonnet, D.
Sigur, N.
Gerdelat, A.
Legrand-Abravanel, F.
Kamar, N.
Afric, L.
REVUE DE MEDECINE INTERNE, 2014, 35 (05): : 333 - 336
[30] Hepatitis E infection in patients with severe acute alcoholic hepatitis
Haim-Boukobza, Stephanie
Coilly, Audrey
Sebagh, Mylene
Bouamoud, Mouna
Antonini, Teresa
Roche, Bruno
Yordanova, Olga
Savary, Janine
Saliba, Faouzi
Duclos-Vallee, Jean-Charles
Samuel, Didier
Ichai, Philippe
Roque-Afonso, Anne-Marie
LIVER INTERNATIONAL, 2015, 35 (03) : 870 - 875

← 1 2 3 4 5 →