An improved one-pot procedure for the synthesis of alkynes from aldehydes

被引:2
|
作者
Muller, S [1 ]
Liepold, B [1 ]
Roth, GJ [1 ]
Bestmann, HJ [1 ]
机构
[1] UNIV ERLANGEN NURNBERG,INST ORGAN CHEM,D-91054 ERLANGEN,GERMANY
关键词
aldehydes; alkynes; dimethyl-1-diazo-2-oxopropylphosphonate;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The transformation of aldehydes to terminal alkynes can be achieved with the reagent dimethyl-1-diazo-2-oxopropylphosphonate 2. The one-pot procedure allows the isolation of the products under very mild conditions in good to excellent yields without requiring low temperatures or inert gas techniques and avoiding the use of strong bases.
引用
收藏
页码:521 / &
页数:3
相关论文
共 50 条
  • [1] A one-pot procedure for the synthesis of alkynes and bromoalkynes from aldehydes
    Michel, P
    Gennet, D
    Rassat, A
    [J]. TETRAHEDRON LETTERS, 1999, 40 (49) : 8575 - 8578
  • [2] A one-pot procedure for the synthesis of iodoalkynes from aldehydes
    Michel, P
    Rassat, A
    [J]. TETRAHEDRON LETTERS, 1999, 40 (49) : 8579 - 8581
  • [3] A one-pot procedure for the synthesis of α-amino phosphonates from alkynes
    Haak, E
    Bytschkov, I
    Doye, S
    [J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2002, 2002 (03) : 457 - 463
  • [4] One-Pot Synthesis of N-H-Free Pyrroles from Aldehydes and Alkynes
    Chen, Lai
    Huo, Jing-Qian
    Si, He-Long
    Xu, Xin-Yu
    Kou, Song
    Mao, Jianyou
    Zhang, Jin-Lin
    [J]. ORGANIC LETTERS, 2021, 23 (11) : 4348 - 4352
  • [5] Multicomponent one-pot procedure for the synthesis of free α-chiral amines from aldehydes
    Côté, A
    Charette, AB
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2005, 70 (26): : 10864 - 10867
  • [6] One-Pot Synthesis of Terminal Alkynes from Alkenes
    Bilanin, Cristina
    Singh, Amravati S.
    Martinez-Belenguer, Lluis
    Leyva-Perez, Antonio
    [J]. JACS AU, 2024, 4 (08): : 3284 - 3294
  • [7] One-pot synthesis of conjugated alkynenitriles from aldehydes
    Kim, Joong-Gon
    Lee, Eun Hwa
    Jang, Doo Ok
    [J]. TETRAHEDRON LETTERS, 2007, 48 (13) : 2299 - 2301
  • [8] A one-pot synthesis of alkynyl sulfides from terminal alkynes
    Zheng, Weixin
    Zheng, Fenfen
    Hong, Ya
    Hu, Linfeng
    [J]. HETEROATOM CHEMISTRY, 2012, 23 (01) : 105 - 110
  • [9] A SIMPLE ONE-POT PROCEDURE FOR SYNTHESIS OF CERTAIN SUBSTITUTED THIOPHENE ALDEHYDES AND KETONES
    MICHAEL, U
    GRONOWIT.S
    [J]. ACTA CHEMICA SCANDINAVICA, 1968, 22 (04): : 1353 - &
  • [10] Stereoselective one-pot synthesis of vinylsilanes from aromatic aldehydes
    Kwan, ML
    Yeung, CW
    Breno, KL
    Doxsee, KM
    [J]. TETRAHEDRON LETTERS, 2001, 42 (08) : 1411 - 1413