A one-pot procedure for the synthesis of alkynes and bromoalkynes from aldehydes

被引：81
|
作者：
Michel, P
Gennet, D
Rassat, A
机构：
[1] Ecole Normale Super, F-75231 Paris 05, France
[2] CNRS, F-75231 Paris, France
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 49期
关键词：
alkynes; bromoalkynes; dibromomethyltriphenylphosphonium bromide; ylids;
D O I：
10.1016/S0040-4039(99)01830-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Alkynes R-C=CH were obtained in good yield through a one-pot procedure by a sequence of reactions starting from a Wittig-type condensation of the aldehydes RCHO with the ylide derived from dibromomethyltriphenylphosphonium bromide 5. The same reactions could also be used to prepare the intermediate dibromoalkenes RCH=CBr2, and in certain cases, the bromoalkynes R-C=CBr. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8575 / 8578
页数：4
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