6th International Immunoglobulin Symposium: Poster presentations

被引:8
|
作者
Fernandez-Cruz, E. [1 ,2 ]
Kaveri, S. V. [3 ]
Peter, H-H. [5 ]
Durandy, A. [4 ]
Cantoni, N. [8 ]
Quinti, I. [11 ]
Sorensen, R. [13 ,14 ]
Bussel, J. B. [15 ]
Danieli, M. G. [12 ]
Winkelmann, A. [6 ]
Bayry, J. [3 ]
Kaesermann, F. [9 ]
Spaeth, P. [10 ]
Helbert, M. [16 ]
Salama, A. [7 ]
van Schaik, I. N. [17 ]
Yuki, N. [18 ]
机构
[1] Univ Complutense, E-28040 Madrid, Spain
[2] Univ Hosp, Madrid, Spain
[3] Univ Paris V Rene Descartes, Necker Hosp, INSERM, Ctr Rech Cordeliers,U872, Paris, France
[4] Univ Paris V Rene Descartes, Necker Hosp, INSERM, U768, Paris, France
[5] Freiburg Univ Hosp, Freiburg, Germany
[6] Univ Rostock, Rostock, Germany
[7] Univ Med Berlin, Charite Campus Virchow Klinikum, Berlin, Germany
[8] Univ Basel Hosp, CH-4031 Basel, Switzerland
[9] CSL Behring AG, Bern, Switzerland
[10] Univ Bern, Bern, Switzerland
[11] Univ Roma La Sapienza, Rome, Italy
[12] Univ Politech Marche, Ancona, Italy
[13] LSU Hlth Sci Ctr, New Orleans, LA USA
[14] Childrens Hosp, New Orleans, LA USA
[15] Cornell Univ, Weill Med Coll, New York, NY 10021 USA
[16] Manchester Royal Infirm, Manchester M13 9WL, Lancs, England
[17] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands
[18] Niigata Natl Hosp, Niigata, Japan
来源
关键词
antibody; autoimmunity; immunodeficiencies; intravenous immunoglobulin; subcutaneous immunoglobulin; REPLACEMENT THERAPY; MANAGEMENT; DEFICIENCY; RISK;
D O I
10.1111/j.1365-2249.2009.04028.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
P>The posters presented at the 6th International Immunoglobulin Symposium covered a wide range of fields and included both basic science and clinical research. From the abstracts accepted for poster presentation, 12 abstracts were selected for oral presentations in three parallel sessions on immunodeficiencies, autoimmunity and basic research. The immunodeficiency presentations dealt with novel, rare class-switch recombination (CSR) deficiencies, attenuation of adverse events following IVIg treatment, association of immunoglobulin (Ig)G trough levels and protection against acute infection in patients with X-linked agammaglobulinaemia (XLA) and common variable immunodeficiency (CVID), and the reduction of class-switched memory B cells in patients with specific antibody deficiency (SAD). The impact of intravenous immunoglobulin on fetal alloimmune thrombocytopenia, pregnancy and postpartum-related relapses in multiple sclerosis and refractory myositis, as well as experiences with subcutaneous immunoglobulin in patients with multi-focal motor neuropathy, were the topics presented in the autoimmunity session. The interaction of dendritic cell (DC)-SIGN and alpha 2,6-sialylated IgG Fc and its impact on human DCs, the enrichment of sialylated IgG in plasma-derived IgG, as wells as prion surveillance and monitoring of anti-measles titres in immunoglobulin products, were covered in the basic science session. In summary, the presentations illustrated the breadth of immunoglobulin therapy usage and highlighted the progress that is being made in diverse areas of basic and clinical research, extending our understanding of the mechanisms of immunoglobulin action and contributing to improved patient care.
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页码:60 / 67
页数:8
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