CONCISE SYNTHESIS OF XYLOKETAL C ANALOGUES

被引：5
|
作者：
Huang, Yan [1 ,2 ]
Lin, Yong-Cheng [2 ]
机构：
[1] Guangzhou Med Coll, Dept Chem, Guangzhou 510182, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China
来源：
HETEROCYCLES | 2009年 / 78卷 / 03期
关键词：
FUNGUS XYLARIA SP; CHINA SEA COAST; RADICAL CYCLIZATION;
D O I：
10.3987/COM-08-11574
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of xyloketal C analogues 12-methylxyloketal C(8) and 12-dehydroxylxyloketal C(11) have been accomplished in three steps, which featured the radical cyclisation as the key step. This is the shortest approach to construct the B C ring systems of the type of ketal skeleton reported to date. The structures of title compounds were elucidated by spectroscopic data and X-ray structure analysis. The final radical cyclisations give mainly the cis-fused anti-substituted stereoisomers.
引用
收藏
页码：749 / 755
页数：7
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