CONCISE SYNTHESIS OF XYLOKETAL C ANALOGUES

被引：5

作者：

Huang, Yan ^{[1
,2
]}

Lin, Yong-Cheng ^{[2
]}

机构：

[1] Guangzhou Med Coll, Dept Chem, Guangzhou 510182, Guangdong, Peoples R China

[2] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China

来源：

HETEROCYCLES | 2009年 / 78卷 / 03期

关键词：

FUNGUS XYLARIA SP; CHINA SEA COAST; RADICAL CYCLIZATION;

D O I：

10.3987/COM-08-11574

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of xyloketal C analogues 12-methylxyloketal C(8) and 12-dehydroxylxyloketal C(11) have been accomplished in three steps, which featured the radical cyclisation as the key step. This is the shortest approach to construct the B C ring systems of the type of ketal skeleton reported to date. The structures of title compounds were elucidated by spectroscopic data and X-ray structure analysis. The final radical cyclisations give mainly the cis-fused anti-substituted stereoisomers.

引用

页码：749 / 755

页数：7

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