Asymmetric aminohydroxylation of heteroaromatic acrylates

被引：0
|
作者：
Raatz, D [1 ]
Innertsberger, C [1 ]
Reiser, O [1 ]
机构：
[1] Univ Regensburg, Inst Organ Chem, D-93040 Regensburg, Germany
来源：
SYNLETT | 1999年 / 12期
关键词：
aminohydroxylations; amino acids; asymmetric catalysis; taxol (TM) (paclitaxel); pyridines;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
N-, S- and O-heteroaromatic acrylates were amino-hydroxylated with generally high regio- and enantioselectivity. While pyridylacrylates are not amenable towards this process, the corresponding N-oxides proved to be a useful substitute, allowing the access to biologically important pyridine substituted taxol(TM) side chain analogs.
引用
收藏
页码：1907 / 1910
页数：4
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