DESIGN, SYNTHESIS AND IN-VITRO EVALUATION OF ATP-COMPETITIVE INHIBITORS OF AURORA KINASE-A USING STRUCTURE-BASED DRUG DESIGN (SBDD)

被引：0
|
作者：
Abdullah, Omeima Alhaj
Mehanna, Ahmed
机构：
来源：
FASEB JOURNAL | 2018年 / 32卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
lb632
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Structure-based design, synthesis, and biological evaluation of novel inhibitors of human cyclophilin A
    Guichou, JF
    Viaud, J
    Mettling, C
    Subra, G
    Lin, YL
    Chavanieu, A
    JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (03) : 900 - 910
  • [42] Structure-based discovery of potent inhibitors of Axl: design, synthesis, and biological evaluation
    Wu, Shuang
    Liao, Min
    Li, Minxiong
    Sun, Mingming
    Xi, Ning
    Zeng, Youlin
    RSC MEDICINAL CHEMISTRY, 2022, 13 (10): : 1246 - 1264
  • [43] Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors
    Scheidt, KA
    Roush, WR
    McKerrow, JH
    Selzer, PM
    Hansell, E
    Rosenthal, PJ
    BIOORGANIC & MEDICINAL CHEMISTRY, 1998, 6 (12) : 2477 - 2494
  • [44] Structure-based design of ATP citrate lyase inhibitors and their anticancer activities
    Jernigan, Finith
    Koerner, Steffi
    Hanai, Jun-ichi
    Sukhatme, Vikas
    Sun, Lijun
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [45] Structure-based drug design of macrocyclic factor XIa inhibitors
    Corte, James
    Fang, Tianan
    Osuna, Honey
    Pinto, Donald
    Rossi, Karen
    Rendina, Alan
    Bozarth, Jeffrey
    Sheriff, Steven
    Myers, Joseph
    Harper, Timothy
    Lou, Zhen
    Zheng, Joanna
    Luettgen, Joseph
    Seiffert, Dietmar
    Lam, Patrick
    Wexler, Ruth
    Quan, Mimi
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [46] Structure-based drug design of HIV protease inhibitors.
    Navia, MA
    Tung, RD
    Chaturvedi, PR
    Rao, BG
    Partaledis, JA
    Kim, EE
    FASEB JOURNAL, 1996, 10 (06): : 2436 - 2436
  • [47] Structure-Based Drug Design Studies on a Series of Aldolase Inhibitors
    Ferreira, Leonardo G.
    dos Santos, Ricardo N.
    Andricopulo, Adriano D.
    JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2013, 24 (02) : 201 - 211
  • [48] Structure-based drug design of TRAF6 inhibitors
    Peng, Zhenghong
    Maxwell, David S.
    Sun, Duoli
    Darnay, Bryant G.
    Bornmann, William G.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [49] STRUCTURE-BASED DRUG DESIGN - INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE
    MONTGOMERY, JA
    EALICK, SE
    BABU, S
    BUGG, CE
    ERION, MD
    GUIDA, WC
    SECRIST, JA
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1993, : 206 - 206
  • [50] STRUCTURE-BASED DRUG DESIGN - INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE
    MONTGOMERY, JA
    FARMACO, 1993, 48 (02): : 297 - 308
12345