DESIGN, SYNTHESIS AND IN-VITRO EVALUATION OF ATP-COMPETITIVE INHIBITORS OF AURORA KINASE-A USING STRUCTURE-BASED DRUG DESIGN (SBDD)

被引：0
|
作者：
Abdullah, Omeima Alhaj
Mehanna, Ahmed
机构：
来源：
FASEB JOURNAL | 2018年 / 32卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
lb632
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Structure-based design, synthesis, and in vitro evaluation of bisubstrate inhibitors for catechol O-methyltransferase (COMT)
    Masjost, B
    Ballmer, P
    Borroni, E
    Zürcher, G
    Winkler, FK
    Jakob-Roetne, R
    Diederich, F
    CHEMISTRY-A EUROPEAN JOURNAL, 2000, 6 (06) : 971 - 982
  • [32] Dihydropyrazole derivatives as telomerase inhibitors: Structure-based design, synthesis, SAR and anticancer evaluation in vitro and in vivo
    Wang, Yang
    Cheng, Fei Xiong
    Yuan, Xiao Long
    Tang, Wen Jian
    Shi, Jing Bo
    Liao, Chen Zhong
    Liu, Xin Hua
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 112 : 231 - 251
  • [33] Structure-based ligand discovery and anti-tumor effects of polo-like kinase-1 atp-competitive inhibitors.
    McInnes, C
    CLINICAL CANCER RESEARCH, 2003, 9 (16) : 6116S - 6116S
  • [34] Structure-based design of cyclin-dependent kinase inhibitors
    Davies, TG
    Pratt, DJ
    Endicott, JA
    Johnson, LN
    Noble, MEM
    PHARMACOLOGY & THERAPEUTICS, 2002, 93 (2-3) : 125 - 133
  • [35] Structure-based Drug Design Using NMR
    Jeeves, Mark
    Quill, Lee
    Overduin, Michael
    EMAGRES, 2015, 4 (02): : 231 - 240
  • [36] Structure-Based Drug Design (SBDD) of allosteric inhibitors for HSC-70 using a combination of pharmacophore searching with ZINCPharmer and AutoDock Vina molecular docking
    Clement, Cristina
    Gonzalez, Janet
    Philipp, Manfred
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [37] Structure-based design and synthesis of aspartyl protease inhibitors
    Ghosh, AK
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U2642 - U2642
  • [38] Structure-based de novo design and biochemical evaluation of novel BRAF kinase inhibitors
    Park, Hwangseo
    Jeong, Yujeong
    Hong, Sungwoo
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (02) : 1027 - 1030
  • [39] ATP site directed kinase inhibition: Prospects for structure-based design
    Clare, M
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 215 : U894 - U894
  • [40] Structure-based design and synthesis of novel pseudosaccharine derivatives as antiproliferative agents and kinase inhibitors
    Elsayed, Mohamed S. A.
    El-Araby, Moustafa E.
    Serya, Rabah A. T.
    El-Khatib, Ahmed H.
    Linscheid, Michael W.
    Abouzid, Khaled A. M.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 61 : 122 - 131
12345