Good outcome after intravenous thrombolysis for acute stroke in a patient under treatment with dabigatran

被引：6
|
作者：
Diogo, Catia [1 ]
Duarte, Josiana [1 ]
Nzwalo, Hipolito [2 ]
Sobral, Sofia [1 ]
Pestana, Paula [3 ]
Rita, Henrique [3 ]
Costa, Jose Sousa e [1 ]
机构：
[1] Unidade Local Saude Litoral Alentejano ULSLA, Dept Internal Med, Santiago, Chile
[2] Ctr Hosp Algarve CHA, Dept Neurol, Natl Inst Med Emergency INEM, Nottingham, England
[3] Natl Inst Med Emergency INEM, Unidade Local Saude Litoral Alentejano, Dept Internal Med, Oporto, Portugal
来源：
AMERICAN JOURNAL OF EMERGENCY MEDICINE | 2014年 / 32卷 / 11期
关键词：
D O I：
10.1016/j.ajem.2014.04.021
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
The novel oral anticoagulants (NOACs) are indicated for stroke and systemic embolism prophylaxis in patients with nonvalvular atrial fibrillation (AF). Very few cases of intravenous recombinant tissue plasminogen activator (IV rt-PA) in patients under treatment with NOACs have been described. The decision to thrombolyze patients under NOACs is complex and requires a balance between the benefits of treatment and the risk of symptomatic hemorrhagic complications. We describe an unusual case of treatment IV rt-PA for acute ischemic stroke in a patient receiving dabigatran for AF. The decision to treat the patient with IV rt-PA was based on the combination of normal coagulation times with the long time elapsed after the last dose of dabigatran, when the drug effect was predictably residual.
引用
收藏
页码：1435 / +
页数：2
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