Good outcome after intravenous thrombolysis for acute stroke in a patient under treatment with dabigatran

被引：6

作者：

Diogo, Catia ^{[1
]}

Duarte, Josiana ^{[1
]}

Nzwalo, Hipolito ^{[2
]}

Sobral, Sofia ^{[1
]}

Pestana, Paula ^{[3
]}

Rita, Henrique ^{[3
]}

Costa, Jose Sousa e ^{[1
]}

机构：

[1] Unidade Local Saude Litoral Alentejano ULSLA, Dept Internal Med, Santiago, Chile

[2] Ctr Hosp Algarve CHA, Dept Neurol, Natl Inst Med Emergency INEM, Nottingham, England

[3] Natl Inst Med Emergency INEM, Unidade Local Saude Litoral Alentejano, Dept Internal Med, Oporto, Portugal

来源：

AMERICAN JOURNAL OF EMERGENCY MEDICINE | 2014年 / 32卷 / 11期

关键词：

D O I：

10.1016/j.ajem.2014.04.021

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The novel oral anticoagulants (NOACs) are indicated for stroke and systemic embolism prophylaxis in patients with nonvalvular atrial fibrillation (AF). Very few cases of intravenous recombinant tissue plasminogen activator (IV rt-PA) in patients under treatment with NOACs have been described. The decision to thrombolyze patients under NOACs is complex and requires a balance between the benefits of treatment and the risk of symptomatic hemorrhagic complications. We describe an unusual case of treatment IV rt-PA for acute ischemic stroke in a patient receiving dabigatran for AF. The decision to treat the patient with IV rt-PA was based on the combination of normal coagulation times with the long time elapsed after the last dose of dabigatran, when the drug effect was predictably residual.

引用

页码：1435 / +

页数：2

共 50 条

[21] Does smoking influence outcome after intravenous thrombolysis for acute ischaemic stroke?
Aries, M. J. H.
Uyttenboogaart, M.
Koch, M. W.
Langedijk, M.
Vroomen, P. C.
Luijckx, G. J.
De Keyser, J.
[J]. EUROPEAN JOURNAL OF NEUROLOGY, 2009, 16 (07) : 819 - 822
[22] Influence of Arterial Occlusion on Outcome After Intravenous Thrombolysis for Acute Ischemic Stroke
Medlin, Friedrich
Amiguet, Michael
Vanacker, Peter
Michel, Patrik
[J]. STROKE, 2015, 46 (01) : 126 - 131
[23] Intravenous Thrombolysis with Recombinant Tissue Plasminogen Activator in a Stroke Patient Treated with Dabigatran
De Smedt, Ann
De Raedt, Sylvie
Nieboer, Koenraad
De Keyser, Jacques
Brouns, Raf
[J]. CEREBROVASCULAR DISEASES, 2010, 30 (05) : 533 - 534
[24] Predictors of good outcome after intravenous tPA for acute ischemic stroke
Demchuk, AM
Tanne, D
Hill, MD
Kasner, SE
Hanson, S
Grond, M
Levine, SR
[J]. NEUROLOGY, 2001, 57 (03) : 474 - 480
[25] Impact of Obesity on Stroke Outcome After Intravenous Thrombolysis
Sarikaya, Hakan
Elmas, Firat
Arnold, Marcel
Georgiadis, Dimitrios
Baumgartner, Ralf W.
[J]. STROKE, 2011, 42 (08) : 2330 - 2332
[26] Intravenous thrombolysis for ischemic stroke in patients receiving dabigatran
Neumann, J.
Macko, J.
Epikova, I.
Stara, M.
Svakova, D.
Bodnarova, P.
Slowik, K.
[J]. CEREBROVASCULAR DISEASES, 2014, 37 : 660 - 660
[27] Does statin in the acute phase of ischemic stroke improve outcome after intravenous thrombolysis?
Fang, Shaokuan
Wu, Jiang
[J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 2012, 312 (1-2) : 195 - 195
[28] Impact of Hemoglobin Levels on the Functional Outcome in Acute Ischemic Stroke after Intravenous Thrombolysis
Kim, Chi Kyung
Jung, Seunguk
Kim, Yerim
Ko, Sang-Bae
Lee, Seung-Hoon
Yoon, Byung-Woo
[J]. CEREBROVASCULAR DISEASES, 2013, 36 : 41 - 41
[29] Lipid profile, statin use, and outcome after intravenous thrombolysis for acute ischaemic stroke
M. Uyttenboogaart
M. W. Koch
K. Koopman
P. C. Vroomen
G. J. Luijckx
J. De Keyser
[J]. Journal of Neurology, 2008, 255 : 875 - 880
[30] Influence of Antiplatelet Pretreatment on the Outcome and Safety after Intravenous Thrombolysis for Acute Ischemic Stroke
Yang, Sunghoon
Kanatsuka, Youichi
Kikyo, Hideyuki
Imazeki, Ryoko
Amari, Kazumitsu
Yamamoto, Masahiro
Nagayama, Masao
[J]. CEREBROVASCULAR DISEASES, 2012, 34 : 73 - 73

← 1 2 3 4 5 →