Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain

被引：9
|
作者：
Nielsen, MS
Petersen, CM
Gliemann, J
Madsen, P
机构：
[1] Department of Medical Biochemistry, University of Aarhus, Bldg. 170, DK-8000 Aarhus C, Ole Worms Allé
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1996年 / 1306卷 / 01期
关键词：
sequencing; bromodomain; transcription factor;
D O I：
10.1016/0167-4781(95)00239-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A 2985 bp cDNA was isolated from a Lambda Zap Express library and sequenced. The cDNA appeared to represent a previously unknown gene that encodes an acidic 757 amino acid protein containing a bromodomain, several potential sites for phosphorylation by casein kinase-II and small proline-rich segments. The results suggest that the encoded protein might be a novel transcription factor.
引用
收藏
页码：14 / 16
页数：3
相关论文
共 50 条
  • [41] A CDNA FROM A MOUSE PANCREATIC BETA-CELL ENCODING A PUTATIVE TRANSCRIPTION FACTOR OF THE INSULIN GENE
    WALKER, MD
    PARK, CW
    ROSEN, A
    ARONHEIM, A
    NUCLEIC ACIDS RESEARCH, 1990, 18 (05) : 1159 - 1166
  • [42] CLONING AND SEQUENCING OF A CDNA-ENCODING A 3RD FLAVIN-CONTAINING MONOOXYGENASE IN RABBITS
    ATTAASAFOADJEI, E
    LAWTON, MP
    PHILPOT, RM
    FASEB JOURNAL, 1991, 5 (04): : A843 - A843
  • [43] Cloning of a cDNA encoding ovine keratinocyte growth factor
    Mitchell, JEA
    McInnes, CJ
    DNA SEQUENCE, 1998, 9 (02): : 121 - 123
  • [44] CLONING AND SEQUENCING OF CDNA-ENCODING THE PUTATIVE INSECT PLASMA-MEMBRANE V-ATPASE SUBUNIT-A
    GRAF, R
    NOVAK, FJS
    HARVEY, WR
    WIECZOREK, H
    FEBS LETTERS, 1992, 300 (02) : 119 - 122
  • [45] CLONING AND SEQUENCING OF THE CDNA-ENCODING A HUMAN TESTIS PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE-PEROXIDASE
    ESWORTHY, RS
    DOAN, K
    DOROSHOW, JH
    CHU, FF
    GENE, 1994, 144 (02) : 317 - 318
  • [46] MOLECULAR-CLONING, SEQUENCING, AND FUNCTIONAL EXPRESSION OF A CDNA-ENCODING HUMAN COPROPORPHYRINOGEN OXIDASE
    MARTASEK, P
    CAMADRO, JM
    DELFAULARUE, MH
    DUMAS, JB
    MONTAGNE, JJ
    DEVERNEUIL, H
    LABBE, P
    GRANDCHAMP, B
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (08) : 3024 - 3028
  • [47] Cloning and sequencing of a human cDNA encoding endothelial P2Y(1) purinoceptor
    Leon, C
    Vial, C
    Cazenave, JP
    Gachet, C
    GENE, 1996, 171 (02) : 295 - 297
  • [48] CLONING AND CHARACTERIZATION OF A HUMAN CDNA-ENCODING A NOVEL PUTATIVE CYTOPLASMIC PROTEIN-TYROSINE-PHOSPHATASE
    TAKEKAWA, M
    ITOH, F
    HINODA, Y
    ARIMURA, Y
    TOYOTA, M
    SEKIYA, M
    ADACHI, M
    IMAI, K
    YACHI, A
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 189 (02) : 1223 - 1230
  • [49] Cloning of the cDNA and localization of the gene encoding human NRBP, a ubiquitously expressed, multidomain putative adapter protein
    Hooper, JD
    Baker, E
    Ogbourne, SM
    Sutherland, GR
    Antalis, TM
    GENOMICS, 2000, 66 (01) : 113 - 118
  • [50] CLONING AND SEQUENCING OF CDNA-ENCODING HUMAN SEPIAPTERIN REDUCTASE - AN ENZYME INVOLVED IN TETRAHYDROBIOPTERIN BIOSYNTHESIS
    ICHINOSE, H
    KATOH, S
    SUEOKA, T
    TITANI, K
    FUJITA, K
    NAGATSU, T
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 179 (01) : 183 - 189
12345