SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF N-SUBSTITUTED BENZIMIDAZOLES

被引：0

作者：

Jadhav, S. B. ^{[1
]}

Shastri, R. A. ^{[1
]}

Bagul, K. R. ^{[1
]}

Gaikwad, K. V. ^{[1
]}

机构：

[1] Milind Coll Sci, PG Dept Chem, Aurangabad 431002, Maharashtra, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2009年 / 18卷 / 03期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two series of benzimidazole derivatives were synthesized by the condensation of different 2-substituted benzimidazoles with 3-(2-chlorophenyl)-5-methylisoxazole-4-carbonylchloride (CMIC) and 3-(2,4-dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride (DCMIC). The synthesized compounds were characterized by IR, H-1 NMR, elemental analysis and their physical properties. The compounds were evaluated for their antibacterial and antifungal activity. All the compounds exhibited significant to moderate antibacterial and antifungal activities.

引用

页码：319 / 320

页数：2

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