Effective Treatment of Human CML By RNAi In Vivo in a Xenotransplantation Mouse Model

被引:2
|
作者
Jyotsana, Nidhi [1 ]
Sharma, Amit [1 ]
Chaturvedi, Anuhar [2 ]
Walsh, Colin [3 ]
Thomas, Anitha [3 ]
Scherr, Michaela [1 ]
Eder, Matthias [2 ]
Battmer, Karin [1 ]
Kuchenbauer, Florian [4 ]
Laszlo, Sajti [5 ]
Barchanski, Annette [5 ]
Goerlich, Kerstin [1 ]
Lindner, Robert [6 ]
Noyan, Fatih [7 ]
Wolfram, Suehs Kurt [8 ]
Grote-Koska, Denis [9 ]
Brand, Korbinian [9 ]
Vornlocher, Hans-Peter [10 ]
Ganser, Arnold [1 ]
Ramsay, Euan [3 ]
Cullis, Pieter [11 ]
Heuser, Michael [1 ]
机构
[1] Hannover Med Sch, Dept Hematol Hemostasis Oncol & Stem Cell Transpl, Hannover, Germany
[2] Hannover Med Sch, Hematol Hemostasis Oncol & SCT, Hannover, Germany
[3] Precis NanoSyst Inc, Vancouver, BC, Canada
[4] Univ Hosp Ulm, Dept Internal Med 3, Ulm, Germany
[5] Laser Zentrum Hannover, Nanotechnol Dept, Hannover, Germany
[6] Hannover Med Sch, Dept Cell Biol, Ctr Anat, Hannover, Germany
[7] Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, Hannover, Germany
[8] Hannover Med Sch, Neurol Clin, Hannover, Germany
[9] Hannover Med Sch, Dept Clin Chem, Hannover, Germany
[10] Axolabs GmbH, Kulmbach, Germany
[11] Precis NanoSyst Inc, Vancouver, BC, Canada
关键词
D O I
10.1182/blood.V126.23.1261.1261
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [41] Beneficial effect of a nitric oxide donor in an ex vivo model of pig-to-human pulmonary xenotransplantation
    Park, Hee Sue
    Kim, Ji-Eun
    You, Hyun Ju
    Gu, Jayoon
    Yoo, Byungsu
    Lee, Saebom
    Lee, Hyun Joo
    Hwang, Ho Young
    Hwang, Yoohwa
    Kim, Hyun Kyung
    Kim, Young Tae
    XENOTRANSPLANTATION, 2015, 22 (05) : 391 - 398
  • [42] Off the shelf' human Treg cells in xenotransplantation of embryonic pig precursor tissues: Simulation in a mouse model
    Tchorsh, Dalit
    Feine, Ilan
    Bachar-Lustig, Esther
    Shezen, Elias
    Reisner, Yair
    XENOTRANSPLANTATION, 2007, 14 (05) : 511 - 512
  • [43] Antiviral RNAi inhalation inhibits human parainfluenza infection ex vivo and in vivo
    Barbosa, Philippe Vollmer
    Dahlmann, Franziska
    Schinke, Maximilian
    Roepken, Fabian
    Steinke, Josi
    Obernolte, Helena
    Beneke, Valerie
    Sewald, Katherina
    Hook, Sebastian
    Ott, Michael
    Schaudien, Dirk
    Schwar, Katharina
    Schwarzer, Adrian
    Schambach, Axel
    Braun, Armin
    EUROPEAN RESPIRATORY JOURNAL, 2024, 64
  • [44] Bcl-2 antisense oligonucleotides chemosensitize human gastric cancer in a SCID mouse xenotransplantation model
    Wacheck, V
    Heere-Ress, E
    Halaschek-Wiener, J
    Lucas, T
    Meyer, H
    Eichler, HG
    Jansen, B
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2001, 79 (10): : 587 - 593
  • [45] Bcl-2 antisense oligonucleotides chemosensitize human gastric cancer in a SCID mouse xenotransplantation model
    Volker Wacheck
    Elisabeth Heere-Ress
    Julius Halaschek-Wiener
    Trevor Lucas
    Hildegard Meyer
    Hans-Georg Eichler
    Burkhard Jansen
    Journal of Molecular Medicine, 2001, 79 : 587 - 593
  • [46] A murine model of HIV encephalitis: xenotransplantation of HIV-infected human neuroglia into SCID mouse brain
    Sanders, VJ
    Mehta, AP
    White, MG
    Achim, CL
    NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 1998, 24 (06) : 461 - 467
  • [47] Luck for Diabetics; Xenotransplantation of β-Cells proven in Mouse-Model
    不详
    DIABETOLOGE, 2012, 8 (04): : 271 - 271
  • [48] Radiolabeled melanin-binding peptides are safe and effective in treatment of human pigmented melanoma in a mouse model of disease
    Dadachova, Ekaterina
    Moadel, Tiffany
    Schweitzer, Andrew D.
    Bryan, Ruth A.
    Zhang, Tong
    Mints, Lisa
    Revskaya, Ekaterina
    Huang, Xianchuan
    Ortiz, Geraldina
    Nosanchuk, Jerome S.
    Nosanchuk, Joshua D.
    Casadevall, Arturo
    CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2006, 21 (02) : 117 - 129
  • [49] IN VIVO AND EX VIVO IMAGING DEMONSTRATE EFFECTIVE INJECTION AND RETENTION OF A COLLAGEN MATRIX IN A MOUSE MODEL OF MYOCARDIAL INFARCTION
    Ahmadi, A.
    Thorn, S.
    Kordos, M.
    Padavan, D. T.
    Hadizad, T.
    Cron, G. O.
    Beanlands, R. S.
    DaSilva, J. N.
    Ruel, M.
    Suuronen, E. I.
    deKemp, R. A.
    CANADIAN JOURNAL OF CARDIOLOGY, 2013, 29 (10) : S307 - S308
  • [50] Effective Theranostic Cyanine for Imaging of Amyloid Species in Vivo and Cognitive Improvements in Mouse Model
    Li, Yinhui
    Chen, Chen
    Xu, Di
    Poon, Chung-Yan
    Ho, See-Lok
    Zheng, Rui
    Liu, Qiong
    Song, Guoli
    Li, Hung-Wing
    Wong, Man Shing
    ACS OMEGA, 2018, 3 (06): : 6812 - 6819