Effective Treatment of Human CML By RNAi In Vivo in a Xenotransplantation Mouse Model

被引:2
|
作者
Jyotsana, Nidhi [1 ]
Sharma, Amit [1 ]
Chaturvedi, Anuhar [2 ]
Walsh, Colin [3 ]
Thomas, Anitha [3 ]
Scherr, Michaela [1 ]
Eder, Matthias [2 ]
Battmer, Karin [1 ]
Kuchenbauer, Florian [4 ]
Laszlo, Sajti [5 ]
Barchanski, Annette [5 ]
Goerlich, Kerstin [1 ]
Lindner, Robert [6 ]
Noyan, Fatih [7 ]
Wolfram, Suehs Kurt [8 ]
Grote-Koska, Denis [9 ]
Brand, Korbinian [9 ]
Vornlocher, Hans-Peter [10 ]
Ganser, Arnold [1 ]
Ramsay, Euan [3 ]
Cullis, Pieter [11 ]
Heuser, Michael [1 ]
机构
[1] Hannover Med Sch, Dept Hematol Hemostasis Oncol & Stem Cell Transpl, Hannover, Germany
[2] Hannover Med Sch, Hematol Hemostasis Oncol & SCT, Hannover, Germany
[3] Precis NanoSyst Inc, Vancouver, BC, Canada
[4] Univ Hosp Ulm, Dept Internal Med 3, Ulm, Germany
[5] Laser Zentrum Hannover, Nanotechnol Dept, Hannover, Germany
[6] Hannover Med Sch, Dept Cell Biol, Ctr Anat, Hannover, Germany
[7] Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, Hannover, Germany
[8] Hannover Med Sch, Neurol Clin, Hannover, Germany
[9] Hannover Med Sch, Dept Clin Chem, Hannover, Germany
[10] Axolabs GmbH, Kulmbach, Germany
[11] Precis NanoSyst Inc, Vancouver, BC, Canada
关键词
D O I
10.1182/blood.V126.23.1261.1261
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [21] Treatment of a Mouse Model of ALS by In Vivo Base Editing
    Lim, Colin K. W.
    Gapinske, Michael
    Brooks, Alexandra K.
    Woods, Wendy S.
    Powell, Jackson E.
    Zeballos, M. Alejandra C.
    Winter, Jackson
    Perez-Pinera, Pablo
    Gaj, Thomas
    MOLECULAR THERAPY, 2020, 28 (04) : 1177 - 1189
  • [22] Effective treatment of ocular HSK with a human apolipoprotein E mimetic peptide in a mouse eye model
    Bhattacharjee, Partha S.
    Neumann, Donna M.
    Foster, Timothy P.
    Clement, Christian
    Singh, Gyanendra
    Thompson, Hilary W.
    Kaufman, Herbert E.
    Hill, James M.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2008, 49 (10) : 4263 - 4268
  • [23] Xenotransplantation as a model for human testicular development
    Hutka, Marsida
    Smith, Lee B.
    Mitchell, Rod T.
    DIFFERENTIATION, 2017, 97 : 44 - 53
  • [24] Xenotransplantation of Human Spermatogonia Into Various Mouse Recipient Models
    Liang, Dongli
    Sun, Qi
    Zhu, Zijue
    Wang, Chuanyun
    Ye, Shicheng
    Li, Zheng
    Wang, Yuan
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 10
  • [25] Ex vivo perfusion of swine lungs:: Lung function in a pig-to-human model of xenotransplantation
    Wiebe, K
    Steinhoff, G
    Poeling, J
    Schröder, C
    Meliss, R
    Winkler, M
    Haverich, A
    TRANSPLANTATION PROCEEDINGS, 2000, 32 (05) : 1149 - 1150
  • [26] In vivo study of extrathymic human T lymphocyte development using a novel xenotransplantation model.
    Wang, XL
    Hong, R
    Nolta, JA
    BLOOD, 2000, 96 (11) : 474A - 474A
  • [27] A Novel Model of Mouse-to-Rat Kidney Xenotransplantation
    Ozcay, N.
    Ozdemir, H.
    TRANSPLANTATION PROCEEDINGS, 2017, 49 (09) : 2204 - 2208
  • [28] Virotherapy of the Malignant U87 Human Glioblastoma in the Orthotopic Xenotransplantation Mouse SCID Model
    S. N. Shchelkunov
    I. A. Razumov
    I. V. Kolosova
    A. V. Romashchenko
    E. L. Zavjalov
    Doklady Biochemistry and Biophysics, 2018, 478 : 30 - 33
  • [29] Virotherapy of the Malignant U87 Human Glioblastoma in the Orthotopic Xenotransplantation Mouse SCID Model
    Shchelkunov, S. N.
    Razumov, I. A.
    Kolosova, I. V.
    Romashchenko, A. V.
    Zavjalov, E. L.
    DOKLADY BIOCHEMISTRY AND BIOPHYSICS, 2018, 478 (01) : 30 - 33
  • [30] Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model
    Thallinger, C
    Wolschek, MF
    Wacheck, V
    Maierhofer, H
    Günsberg, P
    Polterauer, P
    Pehamberger, H
    Monia, BP
    Selzer, E
    Wolff, K
    Jansen, B
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2003, 120 (06) : 1081 - 1086