Discrete Element Modeling (DEM) based investigation of tribocharging in the pharmaceutical powders during hopper discharge

被引:12
|
作者
Mukherjee, Raj [1 ]
Sansare, Sameera [1 ]
Nagarajan, Venkatraman [1 ]
Chaudhuri, Bodhisattwa [1 ,2 ,3 ]
机构
[1] Univ Connecticut, Dept Pharmaceut Sci, Storrs, CT 06269 USA
[2] Univ Connecticut, Dept Chem & Biomol Engn, Storrs, CT 06269 USA
[3] Univ Connecticut, Inst Mat Sci, Storrs, CT 06269 USA
关键词
Tribocharging; Work function; Hopper flow; Discrete Element Modeling;
D O I
10.1016/j.ijpharm.2021.120284
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Triboelectric charging is defined as the phenomenon of charge transfer between two different material surfaces when they are brought into contact and separated. The focus of this research is the development of a Discrete Element Method (DEM) based simulation model to predict tribocharging during hopper discharge. Due to decreased particle-wall interactions and reduced particle wall contact times, net charges generated during hopper discharge are low. The simulation model confirmed this effect and was implemented to predict the triboelectric behavior of glass beads and MCC particles during hopper flow, along with the prediction of percent charged and uncharged particles. Approximately one-third of the particles were predicted to remain uncharged during the hopper discharge simulations for mono-dispersed particles, thus rendering a comparatively high amount of charge distribution into a small concentration of materials. The DEM model acted as a tool to predict charges that can be generated during hopper discharge at a specified geometry, with a potential to mitigate particle charging, when used for appropriate selection of hopper angles, and hopper wall materials.
引用
收藏
页数:8
相关论文
共 50 条
  • [21] Investigation of particle packing in model pharmaceutical powders using X-ray microtomography and discrete element method
    Fu, Xiaowei
    Dutt, Meenakshi
    Bentham, A. Craig
    Hancock, Bruno C.
    Cameron, Ruth E.
    Elliott, James A.
    POWDER TECHNOLOGY, 2006, 167 (03) : 134 - 140
  • [22] Discrete Element Modeling (DEM) of the Vertically Vibrated Particle Bed
    Habib, Muddasar
    Habib, Unsia
    Ahmed, Jamil
    Mohabuth, Nusruth B.
    Langston, Paul
    Miles, Nicolas J.
    Hall, Philip
    PARTICULATE SCIENCE AND TECHNOLOGY, 2014, 32 (03) : 257 - 273
  • [23] The comparison of two domain repartitioning methods used for parallel discrete element computations of the hopper discharge
    Markauskas, Darius
    Kaceniauskas, Arnas
    ADVANCES IN ENGINEERING SOFTWARE, 2015, 84 : 68 - 76
  • [24] Investigation on the uneven distribution of different types of ores in the hopper and stock surface during the charging process of blast furnace based on discrete element method
    Xu, Wenxuan
    Cheng, Shusen
    Niu, Qun
    Hu, Wei
    Bang, Jiawen
    METALLURGICAL RESEARCH & TECHNOLOGY, 2019, 116 (03)
  • [25] Prediction of hopper discharge rate using combined discrete element method and artificial neural network
    Kumar, Raj
    Patel, Chetan M.
    Jana, Arun K.
    Gopireddy, Srikanth R.
    ADVANCED POWDER TECHNOLOGY, 2018, 29 (11) : 2822 - 2834
  • [26] Simulation analysis of fertilizer discharge process using the Discrete Element Method (DEM)
    Bangura, Kemoh
    Gong, Hao
    Deng, Ruoling
    Tao, Ming
    Liu, Chuang
    Cai, Yinghu
    Liao, Kaifeng
    Liu, Jinwei
    Qi, Long
    PLOS ONE, 2020, 15 (07):
  • [27] Discrete element modeling of granular hopper flow of irregular-shaped deformable particles
    Lai, Zhengshou
    Xia, Yidong
    Chen, Qiushi
    ADVANCED POWDER TECHNOLOGY, 2023, 34 (09)
  • [28] Process Modeling in the Pharmaceutical Industry using the Discrete Element Method
    Ketterhagen, William R.
    Ende, Mary T. Am
    Hancock, Bruno C.
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2009, 98 (02) : 442 - 470
  • [29] Discrete element method modeling of non-spherical granular flow in rectangular hopper
    Tao, He
    Jin, Baosheng
    Zhong, Wenqi
    Wang, Xiaofang
    Ren, Bing
    Zhang, Yong
    Xiao, Rui
    CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION, 2010, 49 (02) : 151 - 158
  • [30] Discrete element method modeling of corn-shaped particle flow in rectangular hopper
    Tao H.
    Jin B.
    Zhong W.
    Wang X.
    Frontiers of Architecture and Civil Engineering in China, 2010, 4 (2): : 267 - 275