Synthesis of new heterocyclic dehydroabietylamine derivatives and their biological activity

被引：12
|
作者：
Kovaleva, Kseniya S. [1 ,2 ]
Yarovaya, Olga I. [1 ,2 ]
Shernyukov, Andrey V. [1 ]
Zarubaev, Vladimir V. [3 ]
Shtro, Anna A. [3 ]
Orshanskaya, Yana R. [3 ]
Salakhutdinov, Nariman F. [1 ,2 ]
机构：
[1] Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Lavrentieva Ave, Novosibirsk 630090, Russia
[2] Novosibirsk State Univ, 9 Pirogova St, Novosibirsk 630090, Russia
[3] Res Inst Influenza, Dept Chemotherapy, 17 Prof Popova St, St Petersburg 197376, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2017年 / 53卷 / 03期
基金：
俄罗斯科学基金会;
关键词：
dehydroabietylamine; antibacterial activity; antiviral activity; natural compounds; (+)-DEHYDROABIETYLAMINE; PHTHALIMIDE; OXIDATION; EFFICIENT; PYRROLES;
D O I：
10.1007/s10593-017-2058-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New derivatives of dehydroabietylamine were obtained by transformation of primary amino group to pyrrolidine, piperidine, azepane, morpholine, isoindoline, and pyrrole heterocycles. The obtained compounds were tested for antiviral activity against influenza A/California/07/09 (H1N1)pdm09 strain, as well as the activity against some types of bacteria and fungi.
引用
收藏
页码：364 / 370
页数：7
相关论文
共 50 条
  • [41] New pyridazine derivatives: Synthesis, chemistry and biological activity
    Butnariu, Roxana M.
    Mangalagiu, Ionel I.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (07) : 2823 - 2829
  • [42] Synthesis and biological activity of some new flavone derivatives
    Bozdag-Dündar, O
    Ceylan-Ünlüsoy, M
    Altanlar, N
    Ertan, R
    ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 2005, 55 (02): : 102 - 106
  • [43] Synthesis and biological activity of new melatonin dimeric derivatives
    Di Giacomo, Barbara
    Bedini, Annalida
    Spadoni, Gilberto
    Tarzia, Giorgio
    Fraschini, Franco
    Pannacci, Marilou
    Lucini, Valeria
    BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (13) : 4643 - 4650
  • [44] Synthesis of some new bistriazolidine derivatives and their biological activity
    Yanni, Amal S.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2014, 40 (03) : 350 - 351
  • [45] Synthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidine
    Aziz, Hadil S.
    Al-Araj, Intisar Q.M.
    Abdul-Raheem, Linda R.
    Ahmed, Amena A.
    Journal of the Serbian Chemical Society, 2024, 89 (11) : 1401 - 1410
  • [46] Synthesis and Study Biological Activity of New Heterocyclic Compounds Based on Sugar
    Obaid, Ehab K.
    Abdullah, Rahmah H.
    Hasan, Hussein Abdulkadim
    Hussein, Najlaa N.
    Khalaf, Maha A.
    Radhi, Ali Jabbar
    8TH INTERNATIONAL CONFERENCE ON APPLIED SCIENCE AND TECHNOLOGY (ICAST 2020), 2020, 2290
  • [47] Synthesis and studies on the biological activity of some new spiro heterocyclic compounds
    Khalafallah, AK
    Koraiem, AIM
    AbuDooh, AM
    Shindy, HA
    Elmagid, NA
    ASIAN JOURNAL OF CHEMISTRY, 1996, 8 (03) : 529 - 535
  • [48] New bis-heterocyclic structures: Synthesis, characterization and biological activity
    Farhan, Marwan Mohammed
    Al-Jumaili, Mohammed Hadi Ali
    Bakr, Ekhlas Aziz
    JOURNAL OF CHEMICAL RESEARCH, 2023, 47 (06)
  • [49] Synthesis and Antiacetylcholinesterase Activity of New D-Glyceraldehyde Heterocyclic Derivatives
    Scorzo, Cecilia M.
    Fascio, Mirta L.
    D'Accorso, Norma B.
    Gutierrez Cabrera, Margarita
    Astudillo Saavedra, Luis
    JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2010, 21 (01) : 43 - 48
  • [50] Synthesis of Some New Polycyclic Heterocyclic Compounds of Anticipated Biological Activity
    Alsufyani, Taghreed A.
    Saad, Hosam A.
    Al-otaibi, Asmaa A. A.
    LETTERS IN ORGANIC CHEMISTRY, 2021, 18 (03) : 240 - 249
12345