Synthesis of new heterocyclic dehydroabietylamine derivatives and their biological activity

被引：12
|
作者：
Kovaleva, Kseniya S. [1 ,2 ]
Yarovaya, Olga I. [1 ,2 ]
Shernyukov, Andrey V. [1 ]
Zarubaev, Vladimir V. [3 ]
Shtro, Anna A. [3 ]
Orshanskaya, Yana R. [3 ]
Salakhutdinov, Nariman F. [1 ,2 ]
机构：
[1] Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Lavrentieva Ave, Novosibirsk 630090, Russia
[2] Novosibirsk State Univ, 9 Pirogova St, Novosibirsk 630090, Russia
[3] Res Inst Influenza, Dept Chemotherapy, 17 Prof Popova St, St Petersburg 197376, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2017年 / 53卷 / 03期
基金：
俄罗斯科学基金会;
关键词：
dehydroabietylamine; antibacterial activity; antiviral activity; natural compounds; (+)-DEHYDROABIETYLAMINE; PHTHALIMIDE; OXIDATION; EFFICIENT; PYRROLES;
D O I：
10.1007/s10593-017-2058-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New derivatives of dehydroabietylamine were obtained by transformation of primary amino group to pyrrolidine, piperidine, azepane, morpholine, isoindoline, and pyrrole heterocycles. The obtained compounds were tested for antiviral activity against influenza A/California/07/09 (H1N1)pdm09 strain, as well as the activity against some types of bacteria and fungi.
引用
收藏
页码：364 / 370
页数：7
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