Increased platelet reactivity in patients given Orbofiban after an acute coronary syndrome:: An OPUS-TIMI 16 substudy

被引:75
|
作者
Holmes, MB
Sobel, BE
Cannon, CP
Schneider, DJ
机构
[1] Univ Vermont, Coll Med, Cardiol Unit, Dept Med, Burlington, VT 05401 USA
[2] Brigham & Womens Hosp, Cambridge, MA USA
[3] Harvard Univ, Sch Med, Cambridge, MA 02138 USA
来源
AMERICAN JOURNAL OF CARDIOLOGY | 2000年 / 85卷 / 04期
关键词
D O I
10.1016/S0002-9149(99)00778-X
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The results of the present study underscore the potential value of the use of sensitive assays of specific aspects of platelet function for identifying and quantifying changes in platelet reactivity after initiation of therapy with antiplatelet agents. Implementation of such assays could contribute to optimal design and performance of clinical trials of antiplatelet agents as well as treatment of patients with acute coronary syndromes.
引用
收藏
页码:491 / 493
页数:3
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