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- [8] Statins are associated with lower risk of gastrointestinal bleeding in patients with unstable coronary syndromes: Analysis of the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 (OPUS-TIMI 16) trial AMERICAN HEART JOURNAL, 2006, 151 (05) : 976.e1 - 976.e6