Management of Medication-Related Osteonecrosis of the Jaw

被引：21

作者：

Williams, William Bradford ^{[1
]}

O'Ryan, Felice ^{[1
]}

机构：

[1] Kaiser Permanente, Oakland Med Ctr, Div Maxillofacial Surg, Oakland, CA 94611 USA

来源：

ORAL AND MAXILLOFACIAL SURGERY CLINICS OF NORTH AMERICA | 2015年 / 27卷 / 04期

关键词：

MRONJ; Bisphosphonate; Denosumab; Oral surgery; Maxillofacial surgery; BRONJ; BISPHOSPHONATE-RELATED OSTEONECROSIS; GUIDED BONE RESECTION; SURGICAL RESECTION; HYPERBARIC-OXYGEN; ORAL MICROBIOTA; PENTOXIFYLLINE; FLUORESCENCE; TOCOPHEROL; PROTOCOL; THERAPY;

D O I：

10.1016/j.coms.2015.06.007

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Medication-related osteonecrosis of the jaw (MRONJ) primarily involves patients receiving intravenous bisphosphonates for treatment of skeletal-related malignancies, oral bisphosphonates, and denosumab. There is no consensus regarding the clinical management of MRONJ. Successful treatment may be that which results in a cure, with complete mucosal coverage and elimination of disease, or that which improves the quality of life without a cure (palliation). Helping patients to understand the chronicity and potential progression of the disease is essential to a satisfactory outcome. This review aims to share our treatment approach to patients with MRONJ. Treatment can be divided into medical and surgical therapies.

引用

页码：517 / +

页数：10

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