Management of Medication-Related Osteonecrosis of the Jaw

被引：21
|
作者：
Williams, William Bradford [1 ]
O'Ryan, Felice [1 ]
机构：
[1] Kaiser Permanente, Oakland Med Ctr, Div Maxillofacial Surg, Oakland, CA 94611 USA
来源：
ORAL AND MAXILLOFACIAL SURGERY CLINICS OF NORTH AMERICA | 2015年 / 27卷 / 04期
关键词：
MRONJ; Bisphosphonate; Denosumab; Oral surgery; Maxillofacial surgery; BRONJ; BISPHOSPHONATE-RELATED OSTEONECROSIS; GUIDED BONE RESECTION; SURGICAL RESECTION; HYPERBARIC-OXYGEN; ORAL MICROBIOTA; PENTOXIFYLLINE; FLUORESCENCE; TOCOPHEROL; PROTOCOL; THERAPY;
D O I：
10.1016/j.coms.2015.06.007
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Medication-related osteonecrosis of the jaw (MRONJ) primarily involves patients receiving intravenous bisphosphonates for treatment of skeletal-related malignancies, oral bisphosphonates, and denosumab. There is no consensus regarding the clinical management of MRONJ. Successful treatment may be that which results in a cure, with complete mucosal coverage and elimination of disease, or that which improves the quality of life without a cure (palliation). Helping patients to understand the chronicity and potential progression of the disease is essential to a satisfactory outcome. This review aims to share our treatment approach to patients with MRONJ. Treatment can be divided into medical and surgical therapies.
引用
收藏
页码：517 / +
页数：10
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