Transition-metal-free dehalogenation of aryl halides promoted by phenanthroline/potassium tert-butoxide

被引：19
|
作者：
Liu, Wei [1 ]
Hou, Fanyi [1 ]
机构：
[1] Henan Univ Technol, Coll Food Sci & Technol, Lipid Chem, 100 Lianhua St, Zhengzhou 450001, Peoples R China
来源：
TETRAHEDRON | 2017年 / 73卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Dehalogenation; Aryl halides; Transition-metal-free; Radical; Alkoxy bases; C-H ARYLATION; ELECTRON-TRANSFER REACTIONS; BOND-FORMING REACTIONS; UNACTIVATED ARENES; INTRAMOLECULAR ARYLATION; COUPLING REACTIONS; RADICAL PROCESS; CARBON-CARBON; ACTIVATION; COMPLEXES;
D O I：
10.1016/j.tet.2017.01.002
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Transition-metal-free dehalogenation of various aryl halides (iodides and bromides) can take place efficiently at 70-110 degrees C in the presence of a catalytic amount of 1, 10-phenanthroline and t-BuOK using THF or Dioxane as solvent. Control experiments indicated that radical transfer occurred between aryl radical and alkyl C-H bond to generate alkyl radical. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：931 / 937
页数：7
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