Lithium tert-butoxide mediated α-alkylation of ketones with primary alcohols under transition-metal-free conditions

被引：50
|
作者：
Liang, Yu-Feng [1 ]
Zhou, Xin-Feng [1 ]
Tang, Shi-Ya [2 ]
Huang, Yao-Bing [2 ]
Feng, Yi-Si [1 ]
Xu, Hua-Jian [1 ]
机构：
[1] Hefei Univ Technol, Sch Med Engn, Hefei 230009, Peoples R China
[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China
来源：
RSC ADVANCES | 2013年 / 3卷 / 21期
基金：
中国国家自然科学基金;
关键词：
INDIRECT FRIEDLANDER SYNTHESIS; METHYL KETONES; RUCL2(DMSO)(4) CATALYZES; 2-AMINOBENZYL ALCOHOL; BORROWING HYDROGEN; QUINOLINES; REDUCTION; NANOPALLADIUM; CYCLIZATION; SECONDARY;
D O I：
10.1039/c3ra23221b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
LiOtBu was found to efficiently promote the alpha-alkylation reaction of ketones with primary alcohols, without the addition of any transition metal catalyst.
引用
收藏
页码：7739 / 7742
页数：4
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