A new metabolite with a new substitution pattern from the seeds of the Chinese yew, Taxus mairei

被引:9
|
作者
Huo, Chang-Hong
Wang, Yu-Fang
Zhang, Xi-Ping
Li, Cun-Fang
Shi, Qing-Wen
Kiyota, Hiromasa
机构
[1] Hebei Med Univ, Sch Pharmaceut Sci, Dept Nat Prod Chem, Shijiazhuang 050017, Hebei, Peoples R China
[2] Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Lab Appl Bioorgan Chem,Aoba Ku, Sendai, Miyagi 9818555, Japan
关键词
D O I
10.1002/cbdv.200790009
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A new taxoid metabolite with a new substitution pattern was isolated from the methanol extract of the seeds of Taxus mairei, and its structure was established as 5 alpha,15-dihydroxy-7 beta 9 alpha-diacetoxy-11(15 -> 1)abeo-taxa-4(20),11-dien-13-one (1) on the basis of spectral analysis including H-1- and C-13-NMR, HMQC, HMBC, NOESY, and confirmed by HR-FAB mass spectrometry.
引用
收藏
页码:84 / 88
页数:5
相关论文
共 50 条
  • [31] A NEW TAXANE DERIVATIVE FROM THE HEARTWOOD OF TAXUS-MAIREI
    YEH, MK
    WANG, JS
    LIU, LP
    CHEN, FC
    PHYTOCHEMISTRY, 1988, 27 (05) : 1534 - 1536
  • [32] 2 NEW TAXANE DITERPENOIDS FROM TAXUS-MAIREI
    LIANG, JY
    KINGSTON, DGI
    JOURNAL OF NATURAL PRODUCTS, 1993, 56 (04): : 594 - 599
  • [33] New taxane diterpenoids from the Roots of Taiwanese Taxus mairei
    Shen, YC
    Chang, YT
    Lin, YC
    Lin, CL
    Kuo, YH
    Chen, CY
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (06) : 781 - 787
  • [34] 2 NEW ANTINEOPLASTIC DITERPENES FROM TAXUS-MAIREI
    LIANG, JY
    MIN, ZD
    IINUMA, M
    TANAKA, T
    MIZUNO, M
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1987, 35 (06) : 2613 - 2614
  • [35] Development and characterization of microsatellite markers for the endangered Chinese yew Taxus chinensis var. mairei (Taxaceae)
    Xue, H.
    Lu, C. H.
    Wu, X. B.
    GENETICS AND MOLECULAR RESEARCH, 2012, 11 (02) : 1296 - 1299
  • [36] A new drimane from the heartwood of the Japanese yew, Taxus cuspidata
    Kiyota, H
    Shi, QW
    Oritani, T
    NATURAL PRODUCT LETTERS, 2002, 16 (01): : 21 - 24
  • [37] A new taxane diterpenoid from Taxus chinensis var. mairei
    Zhou, Zhi-Hong
    Qu, Wei
    Liu, Min-Zhuo
    Sun, Jian-Bo
    Wang, Meng-Hua
    Liang, Jing-Yu
    Wu, Fei-Hua
    NATURAL PRODUCT RESEARCH, 2014, 28 (08) : 530 - 533
  • [38] Two new taxanes from Taxus chinensis var. Mairei
    Shi, QW
    Oritani, T
    Sugiyama, T
    Kiyota, H
    PLANTA MEDICA, 1998, 64 (08) : 766 - 769
  • [39] New taxanes with an opened oxetane ring from the roots of Taxus mairei
    Shen, YC
    Lo, KL
    Chen, CY
    Kuo, YH
    Hung, MC
    JOURNAL OF NATURAL PRODUCTS, 2000, 63 (05): : 720 - 722
  • [40] Three novel bicyclic taxane diterpenoids with verticillene skeleton from the needles of Chinese yew, Taxus chinensis var. mairei
    Shi, QW
    Oritani, T
    Sugiyama, T
    PLANTA MEDICA, 1999, 65 (04) : 356 - 359