Tightly regulated gene expression system in Salmonella enterica serovar typhimurium

被引：25
|
作者：
McKinney, J
Guerrier-Takada, C
Galán, J
Altman, S [1 ]
机构：
[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA
[2] Yale Univ, Dept Pediat, Div Infect Dis, New Haven, CT 06510 USA
[3] Yale Univ, Sch Med, Boyer Ctr Mol Med, Sect Microbial Pathogenesis, New Haven, CT 06536 USA
来源：
JOURNAL OF BACTERIOLOGY | 2002年 / 184卷 / 21期
关键词：
D O I：
10.1128/JB.184.21.6056-6059.2002
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A new Salmonella enterica serovar Typhimurium strain has been constructed to facilitate tightly regulated gene expression. Arabinose-inducible and glucose-repressible expression of a T7 RNA polymerase gene that has been integrated with an adjacent araC-P-BAD control element into the bacterial chromosome allows dynamic control of T7 promoter-driven RNA transcription.
引用
收藏
页码：6056 / 6059
页数：4
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