Tightly regulated gene expression system in Salmonella enterica serovar typhimurium

被引：25

作者：

McKinney, J

Guerrier-Takada, C

Galán, J

Altman, S ^{[1
]}

机构：

[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA

[2] Yale Univ, Dept Pediat, Div Infect Dis, New Haven, CT 06510 USA

[3] Yale Univ, Sch Med, Boyer Ctr Mol Med, Sect Microbial Pathogenesis, New Haven, CT 06536 USA

来源：

JOURNAL OF BACTERIOLOGY | 2002年 / 184卷 / 21期

关键词：

D O I：

10.1128/JB.184.21.6056-6059.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A new Salmonella enterica serovar Typhimurium strain has been constructed to facilitate tightly regulated gene expression. Arabinose-inducible and glucose-repressible expression of a T7 RNA polymerase gene that has been integrated with an adjacent araC-P-BAD control element into the bacterial chromosome allows dynamic control of T7 promoter-driven RNA transcription.

引用

页码：6056 / 6059

页数：4

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