Evidence of Henipavirus Infection in West African Fruit Bats

被引:160
|
作者
Hayman, David T. S. [1 ,2 ]
Suu-Ire, Richard [3 ]
Breed, Andrew C. [4 ,5 ]
McEachern, Jennifer A. [5 ,6 ]
Wang, Linfa [5 ,6 ]
Wood, James L. N. [2 ]
Cunningham, Andrew A. [1 ]
机构
[1] Zool Soc London, Inst Zool, London NW1 4RY, England
[2] Univ Cambridge, Cambridge Infect Dis Consortium, Cambridge, England
[3] Wildlife Div Forestry Commission, Accra, Ghana
[4] Univ Queensland, Sch Vet Sci, Brisbane, Qld, Australia
[5] Australian Biosecurity Cooperat Res Ctr, Geelong, Vic, Australia
[6] Australian Anim Hlth Lab, CSIRO Livestock Industries, Geelong, Vic, Australia
来源
PLOS ONE | 2008年 / 3卷 / 07期
关键词
D O I
10.1371/journal.pone.0002739
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Henipaviruses are emerging RNA viruses of fruit bat origin that can cause fatal encephalitis in man. Ghanaian fruit bats (megachiroptera) were tested for antibodies to henipaviruses. Using a Luminex multiplexed microsphere assay, antibodies were detected in sera of Eidolon helvum to both Nipah (39%, 95% confidence interval: 27-51%) and Hendra (22%, 95% CI: 11-33%) viruses. Virus neutralization tests further confirmed seropositivity for 30% (7/23) of Luminex positive serum samples. Our results indicate that henipavirus is present within West Africa.
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页数:4
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