Aniline ortho C-H Sulfuration/Cyclization with Elemental Sulfur for Efficient Synthesis of 2-Substituted Benzothiazoles under Metal-Free Conditions

被引：52
|
作者：
Jiang, Jingjing [1 ]
Li, Guozheng [1 ]
Zhang, Feng [1 ,2 ]
Xie, Hao [1 ]
Deng, Guo-Jun [1 ]
机构：
[1] Xiangtan Univ, Key Lab Green Organ Synth & Applicat Hunan Prov, Key Lab Environm Friendly Chem & Applicat, Minist Educ,Coll Chem, Xiangtan 411105, Peoples R China
[2] Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 08期
基金：
中国国家自然科学基金;
关键词：
2-substituted benzothiazoles; aromatic amines; elemental sulfur; metal-free; CATALYZED REGIOSELECTIVE SULFENYLATION; CONTROLLED SELECTIVE SYNTHESIS; REDOX CONDENSATION REACTION; TRISULFUR RADICAL-ANION; S BOND FORMATION; ARYL SULFIDES; SUBSTITUTED BENZOTHIAZOLES; O-CHLORONITROBENZENES; DIRECT ACCESS; 3-COMPONENT;
D O I：
10.1002/adsc.201701560
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A three-component synthesis of 2-substituted benzothiazoles from aryl amines, elemental sulfur and styrenes or aryl acetylenes in 1-methyl-pyrrolidin-2-one (NMP) is described. Two C-S and one C-N bonds were selectively formed in one-pot under metal-free conditions.
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页码：1622 / 1627
页数：6
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