Exploring the Link between the Germline and Somatic Genome in Cancer

被引:6
|
作者
Geeleher, Paul [1 ]
Huang, R. Stephanie [1 ]
机构
[1] Univ Chicago, Dept Med, Hematol Oncol Sect, Chicago, IL 60637 USA
关键词
BREAST-CANCER; SUSCEPTIBILITY LOCI; METAANALYSES; ASSOCIATION;
D O I
10.1158/2159-8290.CD-17-0192
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Summary: Carter and colleagues propose a systematic analysis of the germline and somatic genome in cancer. They identify interactions that occur between germline and somatic variants. This elucidates the function of the germline genome in the context of cancer risk and development © 2017 American Association for Cancer Research.
引用
收藏
页码:354 / 355
页数:2
相关论文
共 50 条
  • [41] Exploring the link between chronobiology and drug delivery: effects on cancer therapy
    Albuquerque, Tania
    Neves, Ana R.
    Quintela, Telma
    Costa, Diana
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2021, 99 (10): : 1349 - 1371
  • [42] Exploring the link between chronobiology and drug delivery: effects on cancer therapy
    Tânia Albuquerque
    Ana R. Neves
    Telma Quintela
    Diana Costa
    Journal of Molecular Medicine, 2021, 99 : 1349 - 1371
  • [43] Is There a Link Between Genome-Wide Hypomethylation in Blood and Cancer Risk?
    Brennan, Kevin
    Flanagan, James M.
    CANCER PREVENTION RESEARCH, 2012, 5 (12) : 1345 - 1357
  • [44] Cancer aetiology and progression: The crucial link between genome, epigenome and metabolome
    Ibrahim, Salihu Ismail
    Muhammad, Fakhradden Yahya
    NIGERIAN JOURNAL OF BASIC AND CLINICAL SCIENCES, 2020, 17 (02) : 77 - 83
  • [45] Exploring the Link between Helicobacter pylori, Gastric Microbiota and Gastric Cancer
    Sgamato, Costantino
    Rocco, Alba
    Compare, Debora
    Priadko, Kateryna
    Romano, Marco
    Nardone, Gerardo
    ANTIBIOTICS-BASEL, 2024, 13 (06):
  • [46] EXPLORING THE LINK BETWEEN MICROORGANISMS AND ORAL CANCER: A SYSTEMATIC REVIEW OF THE LITERATURE
    Hooper, Samuel J.
    Wilson, Melanie J.
    Crean, St. John
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2009, 31 (09): : 1228 - 1239
  • [47] Review article:: exploring the link between Helicobacter pylori and gastric cancer
    Kuipers, EJ
    ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 1999, 13 : 3 - 11
  • [48] Exploring the link between liver cirrhosis and liver metastasis in colorectal cancer
    Desai, Chaula
    Baskar, Suriya
    Turku, Davin
    Lohani, Sweta
    Vasikaran, Anush
    JOURNAL OF CLINICAL ONCOLOGY, 2025, 43 (4_SUPPL) : 301 - 301
  • [49] Germline contamination and leakage in whole genome somatic single nucleotide variant detection
    Dorota H. Sendorek
    Cristian Caloian
    Kyle Ellrott
    J. Christopher Bare
    Takafumi N. Yamaguchi
    Adam D. Ewing
    Kathleen E. Houlahan
    Thea C. Norman
    Adam A. Margolin
    Joshua M. Stuart
    Paul C. Boutros
    BMC Bioinformatics, 19
  • [50] Germline contamination and leakage in whole genome somatic single nucleotide variant detection
    Sendorek, Dorota H.
    Caloian, Cristian
    Ellrott, Kyle
    Bare, J. Christopher
    Yamaguchi, Takafumi N.
    Ewing, Adam D.
    Houlahan, Kathleen E.
    Norman, Thea C.
    Margolin, Adam A.
    Stuart, Joshua M.
    Boutros, Paul C.
    BMC BIOINFORMATICS, 2018, 19