Efficient metal-free hydrositylation of tertiary, secondary and primary amides to amines

被引：92

作者：

Blondiaux, Enguerrand ^{[1
]}

Cantat, Thibault ^{[1
]}

机构：

[1] CEA, IRAMIS, NIMBE, CNRS UMR 3299, F-91191 Gif Sur Yvette, France

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 66期

基金：

欧洲研究理事会;

关键词：

FREE HYDROGEN ACTIVATION; CATALYZED REDUCTION; CARBON-DIOXIDE; B(C6F5)(3)-CATALYZED HYDROSILATION; CHEMOSELECTIVE REDUCTION; SELECTIVE REDUCTION; HYDROSILYLATION; ORGANOCATALYSIS; ESTERS; CARBOXAMIDES;

D O I：

10.1039/c4cc02894e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Hydrosilylation of secondary and tertiary amides to amines is described using catalytic amounts of B(C6F5)(3). The organic catalyst enables the reduction of amides with cost-efficient, non-toxic and air stable PMHS and TMDS hydrosilanes. The methodology was successfully extended to the more challenging reduction of primary amides.

引用

页码：9349 / 9352

页数：4

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