Highly chemoselective metal-free reduction of tertiary amides

被引：198
|
作者：
Barbe, Guillaume [1 ]
Charette, Andr B. [1 ]
机构：
[1] Univ Montreal, Dept Chim, Montreal, PQ H3C 3J7, Canada
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 01期
关键词：
D O I：
10.1021/ja077463q
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This communication describes the chemoselective metal-free reduction of tertiary amides to the corresponding amines. Hantzsch ester is used as a mild reducing agent for the reduction of trifluoromethanesulfonic anhydride activated amides providing the tertiary amines with high functional group tolerance.
引用
收藏
页码：18 / +
页数：3
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