Facile synthesis of a selectively protected triazamacrocycle

被引:4
|
作者
Skerlj, RT [1 ]
Nan, SQ [1 ]
Zhou, YX [1 ]
Bridger, GJ [1 ]
机构
[1] AnorMED Inc, Langley, BC V2Y 1N5, Canada
关键词
D O I
10.1016/S0040-4039(02)01756-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
1,7-Diaminoheptane was selectively homologated with the novel reagent N-(2-nitrobenzenesulfonyl)aziridine. A series of reactions then followed to afford a selectively protected 14-membered triazamacrocyclic ring. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:7569 / 7571
页数:3
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