Recyclable polymeric π-acid catalyst effective on Mannich-type reaction in water

被引：3
|
作者：
Masaki, Y
Yamazaki, K
Kawai, H
Yamada, T
Itoh, A
Arai, Y
Furukawa, H
机构：
[1] Gifu Pharmaceut Univ, Gifu 5028585, Japan
[2] Meijo Univ, Fac Pharm, Tempaku Ku, Nagoya, Aichi 4688503, Japan
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2006年 / 54卷 / 04期
关键词：
polymer; pi-acid catalyst; aqueous media; Mannich-type reaction; recycle;
D O I：
10.1248/cpb.54.591
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Polymer-supported dicyanolketene acetal (poly-DCKA-1), synthesized by copolymerization of a DCKA bearing a 4-vinylbenzyl group with ethyleneglycol dimethacrylate, was found to be an excellent recyclable catalyst for the three-component Mannich-type reaction of aidehydes, aromatic amines, and TMS enolate of ethyl isobutyrate in water as the sole solvent.
引用
收藏
页码：591 / 593
页数：3
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