Augmentation of Cutaneous Wound Healing by Pharmacologic Mobilization of Endogenous Bone Marrow Stem Cells

被引:3
|
作者
Tolar, Jakub [1 ,2 ]
McGrath, John A. [3 ]
机构
[1] Univ Minnesota, Stem Cell Inst, Minneapolis, MN USA
[2] Univ Minnesota, Div Pediat Blood & Marrow Transplantat, Minneapolis, MN USA
[3] Kings Coll London, St Johns Inst Dermatol, London WC2R 2LS, England
关键词
EPIDERMOLYSIS-BULLOSA; TRANSPLANTATION; FIBROBLASTS; SKIN;
D O I
10.1038/jid.2014.209
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Novel therapeutic tools to accelerate wound healing would have a major impact on the overall burden of skin disease. Lin et al. demonstrate in mice that endogenous bone marrow stem cell mobilization, produced by a pharmacologic combination of AMD3100 and tacrolimus, leads to faster and better-quality wound healing, findings that have exciting potential for clinical translation.
引用
收藏
页码:2312 / 2314
页数:3
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