Augmentation of Cutaneous Wound Healing by Pharmacologic Mobilization of Endogenous Bone Marrow Stem Cells

被引:3
|
作者
Tolar, Jakub [1 ,2 ]
McGrath, John A. [3 ]
机构
[1] Univ Minnesota, Stem Cell Inst, Minneapolis, MN USA
[2] Univ Minnesota, Div Pediat Blood & Marrow Transplantat, Minneapolis, MN USA
[3] Kings Coll London, St Johns Inst Dermatol, London WC2R 2LS, England
关键词
EPIDERMOLYSIS-BULLOSA; TRANSPLANTATION; FIBROBLASTS; SKIN;
D O I
10.1038/jid.2014.209
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Novel therapeutic tools to accelerate wound healing would have a major impact on the overall burden of skin disease. Lin et al. demonstrate in mice that endogenous bone marrow stem cell mobilization, produced by a pharmacologic combination of AMD3100 and tacrolimus, leads to faster and better-quality wound healing, findings that have exciting potential for clinical translation.
引用
收藏
页码:2312 / 2314
页数:3
相关论文
共 50 条
  • [21] Acceleration of Diabetic Wound Healing by Low-Dose Radiation is Associated with Peripheral Mobilization of Bone Marrow Stem Cells
    Guo, Wei-Ying
    Wang, Guan-Jun
    Wang, Ping
    Chen, Qiang
    Tan, Yi
    Cai, Lu
    RADIATION RESEARCH, 2010, 174 (04) : 467 - 479
  • [22] The efficacy of interfollicular epidermal stem cells versus bone marrow-derived mesenchymal stem cells in cutaneous wound healing in diabetic rats
    Kose, Osman
    Pekel, Aysel
    TURK DERMATOLOJI DERGISI-TURKISH JOURNAL OF DERMATOLOGY, 2019, 13 (03): : 117 - 122
  • [23] Role of whole bone marrow, whole bone marrow cultured cells, and mesenchymal stem cells in chronic wound healing
    Rodriguez-Menocal, Luis
    Shareef, Shahjahan
    Salgado, Marcela
    Shabbir, Arsalan
    Van Badiavas, Evangelos
    Stem Cell Research & Therapy, 2015, 6
  • [24] Role of whole bone marrow, whole bone marrow cultured cells, and mesenchymal stem cells in chronic wound healing
    Luis Rodriguez-Menocal
    Shahjahan Shareef
    Marcela Salgado
    Arsalan Shabbir
    Evangelos Van Badiavas
    Stem Cell Research & Therapy, 6
  • [25] Potential benefits of allogeneic bone marrow mesenchymal stem cells for wound healing
    Badiavas, Alexander R.
    Badiavas, Evangelos V.
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2011, 11 (11) : 1447 - 1454
  • [26] Bone marrow cells aid wound healing
    不详
    MOLECULAR THERAPY, 2004, 10 (04) : 611 - 611
  • [27] Exploring the role of stem cells in cutaneous wound healing
    Lau, Katherine
    Paus, Ralf
    Tiede, Stephan
    Day, Philip
    Bayat, Ardeshir
    EXPERIMENTAL DERMATOLOGY, 2009, 18 (11) : 921 - 933
  • [28] The Contribution of Bone Marrow-Derived Mesenchymal Stem Cells to Diabetic Wound Healing
    Shin, Laura
    Peterson, Daniel A.
    DIABETES, 2010, 59 : A50 - A50
  • [29] Role of Endogenous Bone Marrow Stem Cells Mobilization in Repair of Damaged Inner Ear in Rats
    Elbana, Ahmed M.
    Abdel-Salam, Seddik
    Morad, Ghada M.
    Omran, Ahmed A.
    INTERNATIONAL JOURNAL OF STEM CELLS, 2015, 8 (02) : 146 - 154
  • [30] In vivo mobilization of bone marrow mesenchymal stem cells accelerates cutaneous regeneration in epidermolysis bullosa
    Tamai, K.
    Kaneda, Y.
    HUMAN GENE THERAPY, 2013, 24 (12) : A29 - A29