A New Isochroman Derivative from the Marine Fungus Phomopsis sp (No. Gx-4)

被引：8
|
作者：
Yang, Jian Xiang [1 ,3 ]
Qiu, ShengXiang [1 ]
She, Zhigang [2 ]
Lin, Yongcheng [2 ]
机构：
[1] Chinese Acad Sci, South China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China
[3] Guilin Normal Coll, Dept Chem & Engn, Guilin 541002, Guangxi, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2014年 / 50卷 / 03期
基金：
中国国家自然科学基金;
关键词：
natural product; isochroman derivative; marine fungus; bioassays; NMR assignment; CHINA SEA COAST; MANGROVE FUNGUS; METABOLITES;
D O I：
10.1007/s10600-014-0976-y
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A new isochroman, (3R,4S)-3,4-dihydro-8-hydroxy-4-methoxy-3-methylisocoumarin (1), and three known compounds were isolated from the marine fungus Phomopsis sp. (No. Gx-4). Their structures were determined by spectroscopic methods, mainly 1D and 2D NMR. Primary bioassays and preliminary pharmacological tests revealed that compounds 1 and 3 can accelerate the growth of subintestinal vessel plexus (SIV) branches markedly, but compounds 2 and 4 can inhibit their growth.
引用
收藏
页码：424 / 426
页数：3
相关论文
共 50 条
  • [1] A New Isochroman Derivative from the Marine Fungus Phomopsis sp. (No. Gx-4)
    Jian Xiang Yang
    ShengXiang Qiu
    Zhigang She
    Yongcheng Lin
    Chemistry of Natural Compounds, 2014, 50 : 424 - 426
  • [2] A NEW INDENE DERIVATIVE FROM THE MARINE FUNGUS Phomopsis SP (No. GX7-4A)
    Chen, Yiguang
    Pan, Jiahui
    Xu, Fang
    Liu, Fan
    Yang, JianXiang
    Huang, Caihuan
    Xu, Chunling
    Lu, Yongjun
    Cai, Xiaoling
    She, Zhigang
    Lin, Yongcheng
    CHEMISTRY OF NATURAL COMPOUNDS, 2010, 46 (02) : 230 - 232
  • [3] A new isochroman derivative from the marine fungus Phomopsis sp. (No. ZH-111)
    Yang J.X.
    Chen Y.
    Huang C.
    She Z.
    Lin Y.
    Chemistry of Natural Compounds, 2011, 47 (1) : 13 - 16
  • [4] A NEW ISOCHROMAN DERIVATIVE FROM THE MARINE FUNGUS Phomopsis sp. (No. ZH-111)
    Yang, Jian Xiang
    Chen, Yiguang
    Huang, Caihuan
    She, Zhigang
    Lin, Yongcheng
    CHEMISTRY OF NATURAL COMPOUNDS, 2011, 47 (01) : 13 - 16
  • [5] A new indene derivative from the marine fungus Phomopsis SP. (No. GX7-4A)
    Yiguang Chen
    Jiahui Pan
    Fang Xu
    Fan Liu
    JianXiang Yang
    Caihuan Huang
    Chunling Xu
    Yongjun Lu
    Xiaoling Cai
    Zhigang She
    Yongcheng Lin
    Chemistry of Natural Compounds, 2010, 46 : 230 - 232
  • [6] A new xanthone derivative from the marine fungus Phomopsis sp (No. SK7RN3G1)
    Yang, Jian Xiang
    Qiu, ShengXiang
    She, Zhigang
    Lin, Yongcheng
    CHEMISTRY OF NATURAL COMPOUNDS, 2013, 49 (02) : 246 - 248
  • [7] A new xanthone derivative from the marine fungus Phomopsis sp (No. SK7RN3G1)
    Yang, Jian Xiang
    Qiu, ShengXiang
    She, Zhigang
    Lin, Yongcheng
    CHEMISTRY OF NATURAL COMPOUNDS, 2013, 49 (01) : 31 - 33
  • [8] A new xanthone derivative from the marine fungus Phomopsis sp. (No. SK7RN3G1)
    Jian Xiang Yang
    ShengXiang Qiu
    Zhigang She
    Yongcheng Lin
    Chemistry of Natural Compounds, 2013, 49 : 246 - 248
  • [9] A new xanthone derivative from the marine fungus Phomopsis sp. (No. SK7RN3G1)
    Jian Xiang Yang
    ShengXiang Qiu
    Zhigang She
    Yongcheng Lin
    Chemistry of Natural Compounds, 2013, 49 : 31 - 33
  • [10] A new anthraquinone derivative from the marine endophytic fungus Fusarium sp (No. b77)
    Shao, Changlun
    Wang, Changyun
    Zheng, Caijuan
    She, Zhigang
    Gu, Yucheng
    Lin, Yongcheng
    NATURAL PRODUCT RESEARCH, 2010, 24 (01) : 81 - 85
12345