A new xanthone derivative from the marine fungus Phomopsis sp. (No. SK7RN3G1)

被引:0
|
作者
Jian Xiang Yang
ShengXiang Qiu
Zhigang She
Yongcheng Lin
机构
[1] Chinese Academy of Sciences,Key Laboratory of Plant Resources Conservation and Sustainable Utilization
[2] Sun Yat-Sen University,School of Chemistry and Chemical Engineering
来源
Chemistry of Natural Compounds | 2013年 / 49卷
关键词
natural product; xanthone derivative; marine fungus; bioassays; NMR assignmen.;
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中图分类号
学科分类号
摘要
A new xanthone, 2,6-dihydroxy-3-methyl-9-oxoxanthene-8-carboxylic acid methyl ester (1), and three known compounds were isolated from the marine fungus Phomopsis sp. (No. SK7RN3G1). Their structures were determined by spectroscopic methods, mainly 1D and 2D NMR. Primary bioassays showed that 1 exhibited cytotoxicity against HEp-2 and HepG2 cells with IC50 values of 8 and 9 μg/mL, respectively.
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页码:31 / 33
页数:2
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