Single-Photon Avalanche Diode CMOS Sensor for Time-Resolved Fluorescence Measurements

被引:95
|
作者
Stoppa, David [1 ]
Mosconi, Daniel [1 ]
Pancheri, Lucio [1 ]
Gonzo, Lorenzo [1 ]
机构
[1] Fdn Bruno Kessler, Ctr Ric Sci & Tecnol FBK irst, I-38100 Povo, TN, Italy
关键词
CMOS; fluorescence lifetime; single-photon avalanche diode (SPAD); time-gating; ARRAY;
D O I
10.1109/JSEN.2009.2025581
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
A single-photon avalanche diode-based pixel array for the analysis of fluorescence phenomena is presented. Each 180 x 150 mu m(2) pixel integrates a single photon detector combined with an active quenching circuit and a 17-bit digital events counter. On-chip master logic provides the digital control phases required by the pixel array with a full programmability of the main timing synchronisms. The pixel exhibits an average dark count rate of 3 kcps and a dynamic range of over 120-dB in time uncorrelated operation. A complete characterization of the single photon avalanche diode characteristics is reported. Time-resolved fluorescence measurements have been demonstrated by detecting the fluorescence decay of quantum-dot samples without the aid of any optical filters for excitation laser light cutoff.
引用
收藏
页码:1084 / 1090
页数:7
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