Two new Daphniphyllum alkaloids from Daphniphyllum macropodum Miq.

被引：5
|
作者：
Li, Zhen-Yu [1 ]
Xu, Hong-Gui [2 ]
Zhao, Zhong-Zhen [2 ]
Guo, Yue-Wei [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200031, Peoples R China
[2] Hong Kong Baptist Univ, Sch Chinese Med, Kowloon, Hong Kong, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2009年 / 11卷 / 02期
关键词：
Daphniphyllum macropodum Miq; alkaloids; cytotoxicity; SKELETONS; CALYCINUM; CASCADE;
D O I：
10.1080/10286020802618837
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new Daphniphyllum alkaloids, 4,21-deacetyl-deoxyyuzurimine (1) and macropodumine L (2), together with the two known related alkaloids, have been isolated from the bark of Daphniphyllum macropodum Miq. The structures of the new compounds were elucidated on the basis of the detailed analysis of spectroscopic data, chemical method, and by comparison of the spectroscopic data with those of known compounds. Compounds 2 and 4 exhibited weak cytotoxicity against human carcinoma cell lines SMMC-7721 and HO-8910.
引用
收藏
页码：153 / 158
页数：6
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