Two new Daphniphyllum alkaloids from Daphniphyllum macropodum Miq.

被引：5
|
作者：
Li, Zhen-Yu [1 ]
Xu, Hong-Gui [2 ]
Zhao, Zhong-Zhen [2 ]
Guo, Yue-Wei [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200031, Peoples R China
[2] Hong Kong Baptist Univ, Sch Chinese Med, Kowloon, Hong Kong, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2009年 / 11卷 / 02期
关键词：
Daphniphyllum macropodum Miq; alkaloids; cytotoxicity; SKELETONS; CALYCINUM; CASCADE;
D O I：
10.1080/10286020802618837
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new Daphniphyllum alkaloids, 4,21-deacetyl-deoxyyuzurimine (1) and macropodumine L (2), together with the two known related alkaloids, have been isolated from the bark of Daphniphyllum macropodum Miq. The structures of the new compounds were elucidated on the basis of the detailed analysis of spectroscopic data, chemical method, and by comparison of the spectroscopic data with those of known compounds. Compounds 2 and 4 exhibited weak cytotoxicity against human carcinoma cell lines SMMC-7721 and HO-8910.
引用
收藏
页码：153 / 158
页数：6
相关论文
共 50 条
  • [21] ISOLATION OF 2 NEW ALKALOIDS - FROM DAPHNIPHYLLUM MACROPODUM MIQUEL
    IRIKAWA, H
    SAKURAI, H
    SAKABE, N
    HIRATA, Y
    TETRAHEDRON LETTERS, 1966, (44) : 5363 - &
  • [22] Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum
    Cao, Mingming
    Zhang, Yu
    He, Hongping
    Li, Shifei
    Huang, Shendian
    Chen, Duozhi
    Tang, Guihua
    Li, Shunlin
    Di, Yingtong
    Hao, Xiaojiang
    JOURNAL OF NATURAL PRODUCTS, 2012, 75 (06): : 1076 - 1082
  • [23] A zwitterionic alkaloid, containing a rare cyclopentadienyl anion unit, from the stem barks of Daphniphyllum macropodum MiQ.
    Gan, Xian-Wen
    Bai, Hai-Yun
    Chen, Qi-Gang
    Ma, Lei
    Hu, Li-Hong
    CHEMISTRY & BIODIVERSITY, 2006, 3 (11) : 1255 - 1259
  • [24] Daphnimacropodines A-D, alkaloids from Daphniphyllum macropodum
    Kong, Ning-Chuan
    He, Hong-Ping
    Wang, Yue-Hu
    Mu, Shu-Zhen
    Di, Ying-Tong
    Hao, Xiao-Jiang
    JOURNAL OF NATURAL PRODUCTS, 2007, 70 (08): : 1348 - 1351
  • [25] Two New Daphniphyllum Alkaloids from the Stems and Leaves of Daphniphyllum calycinum
    Li, Zhen-Yu
    Peng, Shu-Ying
    Fang, Li
    Yang, Yi-Ming
    Guo, Yue-Wei
    CHEMISTRY & BIODIVERSITY, 2009, 6 (01) : 105 - 110
  • [26] Daphmacromines K-O, alkaloids from Daphniphyllum macropodum
    Cao, Ming-Ming
    Wang, Lei
    Zhang, Yu
    He, Hong-Ping
    Gu, Yu-Cheng
    Zhang, Qiang
    Li, Yan
    Yuan, Chun-Mao
    Li, Shun-Lin
    Di, Ying-Tong
    Hao, Xiao-Jiang
    FITOTERAPIA, 2013, 89 : 205 - 209
  • [27] Chemical constituents from Daphniphyllum macropodum
    Lu, Yun-Yang
    Wang, Xiao-Yang
    Gao, Kai
    Zhang, Wei
    Tang, Hai-Feng
    Chen, Jian-Zong
    BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2014, 57 : 458 - 460
  • [28] Hydroxylated Daphniphyllum Alkaloids from Daphniphyllum himalense
    Zhang, Hua
    Shyaula, Sajan L.
    Li, Jing-Ya
    Li, Jia
    Yue, Jian-Min
    JOURNAL OF NATURAL PRODUCTS, 2015, 78 (11): : 2761 - 2767
  • [29] Daphniphyllum and diterpenoid alkaloids from Daphniphyllum longeracemosum
    Li, Chun-Shun
    Di, Ying-Tong
    Mu, Shu-Zhen
    He, Hong-Ping
    Zhang, Qiang
    Fang, Xin
    Zhang, Yu
    Li, Shun-Lin
    Lu, Yang
    Gong, Yan-Qing
    Hao, Xiao-Jiang
    JOURNAL OF NATURAL PRODUCTS, 2008, 71 (07): : 1202 - 1206
  • [30] New alkaloids from Daphniphyllum himalense
    Zhang, Hua
    Zhang, Dong-Dong
    Li, Jing-Ya
    Shyaula, Sajan L.
    Li, Jia
    Yue, Jian-Min
    RSC ADVANCES, 2016, 6 (50): : 44402 - 44409
12345