Oleanane-Type Isomeric Triterpenoids from Barringtonia racemosa

被引：21
|
作者：
Gowri, P. Mangala [1 ]
Radhakrishnan, S. V. S. [1 ]
Basha, S. Jeelani [2 ]
Sarma, A. V. S. [2 ]
Rao, J. Madhusudana [1 ]
机构：
[1] Indian Inst Chem Technol, Nat Prod Lab, Hyderabad 500607, Andhra Pradesh, India
[2] Indian Inst Chem Technol, NMR Div, Hyderabad 500607, Andhra Pradesh, India
来源：
JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 04期
关键词：
SAPONINS; EXTRACT; BARK;
D O I：
10.1021/np8007396
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new isomeric acylated oleanane-type triterpenoids along with three known compounds were isolated from the MeOH extract of the dried fruits of Barringtonia racemosa. On the basis of spectroscopic methods, with special emphasis on 1D and 2D NMR techniques as well as chemical methods, the structures were characterized as racemosol A (1) [22 alpha-acetoxy-3 beta,15 alpha, 16 alpha,21 beta-tetrahydroxy-28-(2-methylbutyryl)olean-12-ene] and iscracemosol A (2) [21 beta-acetoxy-3 beta,15 alpha, 16 alpha,28-tetrahydroxy-22 alpha-(2-methylbutyryl)olean-12-ene]. The isolated compounds (1-5) were not active against HeLa and P388 D1 carcinoma cell lines.
引用
收藏
页码：791 / 795
页数：5
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