The potential clinical applications and prospects of microRNAs in lung cancer

被引：15
|
作者：
Gao, Ying [1 ]
Gao, Fei [2 ]
Ma, Jin-lu [1 ]
Sun, Wen-ze [1 ]
Song, Li-ping [1 ]
机构：
[1] Xi An Jiao Tong Univ, Coll Med, Affiliated Hosp 1, Dept Radiotherapy Oncol, Xian 710061, Peoples R China
[2] Xian Med Univ, Affiliated Hosp 1, Dept Neurol, Xian, Peoples R China
来源：
ONCOTARGETS AND THERAPY | 2014年 / 7卷
基金：
中国国家自然科学基金;
关键词：
microRNA; lung cancer; biomarker; chemotherapy; radiotherapy; TUMOR-SUPPRESSOR; EXPRESSION; CELLS; SENSITIVITY; RESISTANCE; GROWTH; RADIOSENSITIVITY; CHEMORESISTANCE; PROLIFERATION; PATHOGENESIS;
D O I：
10.2147/OTT.S62227
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost half of all genes are regulated by microRNAs (miRNAs). This review focuses on the role of miRNAs in lung cancer and also touches on the value of miRNA-based novel therapies for lung cancers.
引用
收藏
页码：901 / 905
页数：5
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