The potential clinical applications and prospects of microRNAs in lung cancer

被引：15
|
作者：
Gao, Ying [1 ]
Gao, Fei [2 ]
Ma, Jin-lu [1 ]
Sun, Wen-ze [1 ]
Song, Li-ping [1 ]
机构：
[1] Xi An Jiao Tong Univ, Coll Med, Affiliated Hosp 1, Dept Radiotherapy Oncol, Xian 710061, Peoples R China
[2] Xian Med Univ, Affiliated Hosp 1, Dept Neurol, Xian, Peoples R China
来源：
ONCOTARGETS AND THERAPY | 2014年 / 7卷
基金：
中国国家自然科学基金;
关键词：
microRNA; lung cancer; biomarker; chemotherapy; radiotherapy; TUMOR-SUPPRESSOR; EXPRESSION; CELLS; SENSITIVITY; RESISTANCE; GROWTH; RADIOSENSITIVITY; CHEMORESISTANCE; PROLIFERATION; PATHOGENESIS;
D O I：
10.2147/OTT.S62227
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost half of all genes are regulated by microRNAs (miRNAs). This review focuses on the role of miRNAs in lung cancer and also touches on the value of miRNA-based novel therapies for lung cancers.
引用
收藏
页码：901 / 905
页数：5
相关论文
共 50 条
  • [31] The clinical potential of microRNAs
    Budhu, Anuradha
    Ji, Junfang
    Wang, Xin W.
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2010, 3
  • [32] The clinical potential of microRNAs
    Anuradha Budhu
    Junfang Ji
    Xin W Wang
    Journal of Hematology & Oncology, 3
  • [33] Lung cancer and microRNAs
    Hampton, T
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2006, 295 (16): : 1889 - 1889
  • [34] Liquid Biopsies in Lung Cancer: Four Emerging Technologies and Potential Clinical Applications
    Chudasama, Dimple
    Katopodis, Periklis
    Stone, Nick
    Haskell, Jennifer
    Sheridan, Hannah
    Gardner, Benjamin
    Urnovitz, Howard
    Schuetz, Ekkehard
    Beck, Julia
    Hall, Marcia
    Barr, James
    Sisu, Cristina
    Rice, Alexandra
    Polychronis, Andreas
    Anikin, Vladimir
    Karteris, Emmanouil
    CANCERS, 2019, 11 (03):
  • [35] MicroRNAs in lung cancer
    Castro, Diana
    Moreira, Marcia
    Gouveia, Alexandra Monteiro
    Pozza, Daniel Humberto
    De Mello, Ramon Andrade
    ONCOTARGET, 2017, 8 (46) : 81679 - 81685
  • [36] MicroRNAs and lung cancer
    Zamani, Ayse Gul
    Zamani, Adil
    TUBERKULOZ VE TORAKS-TUBERCULOSIS AND THORAX, 2013, 61 (01): : 57 - 62
  • [37] microRNAs and lung cancer
    Slack, Frank J.
    CLINICAL CANCER RESEARCH, 2012, 18 (03)
  • [38] MICRORNAS IN LUNG CANCER
    Skrzypski, M.
    JOURNAL OF THORACIC ONCOLOGY, 2010, 5 (05) : S27 - S27
  • [39] MicroRNAs and long non-coding RNAs in pancreatic cancer: From epigenetics to potential clinical applications
    Bravo-Vazquez, Luis Alberto
    Frias-Reid, Natalia
    Ramos-Delgado, Ana Gabriela
    Osorio-Perez, Sofia Madeline
    Zlotnik-Chavez, Hania Ruth
    Pathak, Surajit
    Banerjee, Antara
    Bandyopadhyay, Anindya
    Duttaroy, Asim K.
    Paul, Sujay
    TRANSLATIONAL ONCOLOGY, 2023, 27
  • [40] Clinical Efficacy and Future Prospects of Immunotherapy in Lung Cancer
    Kinoshita, Tomonari
    Terai, Hideki
    Yaguchi, Tomonori
    LIFE-BASEL, 2021, 11 (10):
12345