Endothelium and Vascular Smooth Muscle Cells in the Context of Uremia

被引：23

作者：

Guenthner, Thomas ^{[1
]}

Jankowski, Vera ^{[1
]}

Kretschmer, Axel ^{[2
]}

Nierhaus, Marc ^{[1
]}

van der Giet, Markus ^{[1
]}

Zidek, Walter ^{[1
]}

Jankowski, Joachim ^{[1
]}

机构：

[1] Charite, Med Klin 4, CBF, D-12200 Berlin, Germany

[2] Bayer Schering Pharma, Global Drug Discovery Translat Med & Biomarkers, Wuppertal, Germany

来源：

SEMINARS IN DIALYSIS | 2009年 / 22卷 / 04期

关键词：

CHRONIC KIDNEY-DISEASE; NITRIC-OXIDE; ASYMMETRICAL DIMETHYLARGININE; OXIDATIVE STRESS; GROWTH-FACTOR; ANGIOTENSIN; RISK; ADRENOMEDULLIN; PROLIFERATION; ANGIOGENESIS;

D O I：

10.1111/j.1525-139X.2009.00594.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

It is obvious that retention of uremic toxins leads to endothelial dysfunction, which in turn initiates proliferation of vascular smooth muscle cells. Yet, the entity of the cascade of pathomechanisms has not sufficiently been elucidated. Endothelial dysfunction inevitably and irreversibly leads to progressive cardiovascular dysfunction and thereby represents the beginning of a life-limiting cascade. This review highlights important findings in this field.

引用

页码：428 / 432

页数：5

共 50 条

[31] Smoothelin in vascular smooth muscle cells
van Eys, Guillaume J.
Niessen, Petra M.
Rensen, Sander S.
TRENDS IN CARDIOVASCULAR MEDICINE, 2007, 17 (01) : 26 - 30
[32] Vascular smooth muscle cells in atherosclerosis
Basatemur, Gemma L.
Jorgensen, Helle F.
Clarke, Murray C. H.
Bennett, Martin R.
Mallat, Ziad
NATURE REVIEWS CARDIOLOGY, 2019, 16 (12) : 727 - 744
[33] Smooth Muscle Cells for Vascular Engineering
Chen, Y. Eugene
Xie, Changqing
Hamblin, Milton
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2011, 31 (12) : 2772 - 2774
[34] MICRORNA AND VASCULAR SMOOTH MUSCLE CELLS
Xie, Changqing
Zhang, Jifeng
Chen, Y. Eugene
VITAMINS AND HORMONES: STEM CELL REGULATORS, 2011, 87 : 321 - 339
[35] Vascular Smooth Muscle Cells in Atherosclerosis
Bennett, Martin R.
Sinha, Sanjay
Owens, Gary K.
CIRCULATION RESEARCH, 2016, 118 (04) : 692 - 702
[36] Vascular smooth muscle cells in atherosclerosis
Gemma L. Basatemur
Helle F. Jørgensen
Murray C. H. Clarke
Martin R. Bennett
Ziad Mallat
Nature Reviews Cardiology, 2019, 16 : 727 - 744
[37] Smooth Muscle Cells in Vascular Remodeling
Shi, Ning
Mei, Xiaohan
Chen, Shi-You
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2019, 39 (12) : E247 - E252
[38] ENDOTHELIUM PERICYTES AND SMOOTH MUSCLE - 3 CONTRACTILE CELLS
MAJNO, G
AMERICAN JOURNAL OF PATHOLOGY, 1968, 52 (06): : A61 - &
[39] Cyclosporine A stimulates proliferation of vascular smooth muscle cells and enhances monocyte adhesion to vascular smooth muscle cells
Hu, SJ
Fernandez, R
Jones, JW
TRANSPLANTATION PROCEEDINGS, 1999, 31 (1-2) : 663 - 665
[40] Simulated microgravity reduces vascular contractility: Role of vascular smooth muscle versus endothelium
Sara, D
Duckles, SP
Krause, DN
Loyola, SM
Purdy, RE
FASEB JOURNAL, 1997, 11 (03): : 1401 - 1401

← 1 2 3 4 5 →